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Prednisolone Acetate Prednisolone cas 52-21-1
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Name:Prednisolone Acetate
CAS:52-21-1
Description
Prednisolone Acetate 52-21-1
Prednisolone acetate is mainly used in rheumatoid arthritis, rheumatic fever, Lupus Erythematosus, Scleroderma, Dermatomyositis, acute lymphatic leukemia.
Application
1. Prednisolone acetate ophthalimic suspension (eye drops) is an adrenocortical steroid product, prepared as a sterile opthalmic suspension and used to reduce swellig, redness, itching, and allergic reactions affecting the eye.
2. Prednisolone acetate is used as an antiallergic and immunosuppressive drug and as an anti-inflammatory agent in the treatment of rheumatoid arthritis.
Items | Specifications | Results |
Character | White or almost white crystallin powder | Almost white crystalline powder |
Specific rotation | +112°~+119° | +118.3° |
Identification | 1) Complies by IR | Conforms |
2) Complies by UV not more than 2.5% | 1.20% | |
3) Positive reaction | Conforms | |
Chromatographic purity | Principal impurity not more than 1.0% | 0.32% |
Total impurities not more than 2.0% | 0.69% | |
Methanol | ≤3000ppm | 438ppm |
Pyridine | ≤200ppm | 31ppm |
Loos on drying | Not more than 1.0% | 0.10% |
Assay | Contains 97.0% to 102.0% of C23H306 calculated on dried basis | 100.40% |
Conclusion | The results can conforms with USP32 |
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