Levonorgestrel Levonorgestrel powder cas 797-63-7
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Levonorgestrel is a second-generation progestin and is the most widely prescribed contraceptive progestin worldwide. It has high progestational and androgenic effects. Levonorgestrel negatively affects serum lipoproteins.
Levonorgestrel is used both as an emergency contraceptive as well as for long-term prevention of pregnancy. For the former it can be administered as an oral tablet after unprotected sexual intercourse. One 0.75 mg tablet should be taken as soon as possible within 72 hours of intercourse and a second 0.75 mg tablet should be taken 12 hours after the first dose.
For long-term pregnancy prevention and Intra-uterine system is inserted into the uterine cavity which releases 20 mcg Levonorgestrel/day over 5 years. It may be removed and replaced with a new unit at anytime during menstrual cycle.
Name |
Levonorgestrel |
Synonyms |
D(-)-13beta-Ethyl-17alpha-ethynyl-17beta-hydroxygon-4-en-3-one |
Brand |
Salus |
Molecular Formula |
C21H28O2 |
Molecular Weight |
312.45 |
CAS Registry Number |
797-63-7 |
EINECS |
212-349-8 |
COA
ITEMS |
STANDARDS |
RESULTS |
IDENTIFICATION |
AS STIPULATED |
CONFORM |
MELTING POINT |
BETWEEN 232°C AND 239°C |
236°C-238°C |
SPECIFIC ROTATION |
BETWEEN -30° AND -35° |
-33° |
LOSS ON DRYING |
NOT MORE THAN 0.5% |
0.1% |
RESIDUE ON IGNITION |
NOT MORE THAN 0.3% |
0.05% |
ETHYNYL GROUP |
BETWEEN 7.81% AND 8.18% |
7.94% |
CHROMATOGRAPHIC PURITY |
AS STIPULATED |
CONFORM |
ASSAY |
BETWEEN 98.0% AND 102.0% |
99.0% |
RESIDUAL SOLVENTS |
|
|
ETHANOL |
NOT MORE THAN 3000PPM |
719.3PPM |
ETHYL ACETATE |
NOT MORE THAN 3000PPM |
461.5PPM |
CONCLUSION |
CONFORMS WITH USP30 |
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