Loteprednol etabonate Loteprednol cas 82034-46-6
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basic information: CAS: 82034-46-6 Loteprednol etabonate
Product Name | Loteprednol etabonate |
Synonyms | LOTEPREDNOL ETABONATE;chloromethyl 17-ethoxycarbonyloxy-11-hydroxy-10,13-dimethyl-3-oxo-7,8,9,11,12,14,15,16-octahydro-6h-cyclopenta[a]phenanthrene-17-carboxylate;CDDD-5604, HGP-1, P-5604, Alrex, Lotemax;Androsta-1,4-diene-17-carboxylicacid,17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-,chloromethylester,;Androsta-1,4-diene-17-carboxylic acid, 17-[(ethoxycarbonyl)oxy]-11-hydroxy-3-oxo-, chloromethyl ester, (11b,17a)-;Lotemax;17α-(Ethoxycarbonyloxy)-11β-hydroxy-3-oxoandrosta-1,4-diene-17-carboxylic acid chloromethyl ester;17α-(Ethoxycarbonyloxy)-11β-hydroxy-3-oxoandrosta-1,4-diene-17β-carboxylic acid chloromethyl ester |
CAS | 82034-46-6 |
MF | C24H31ClO7 |
MW | 466.95 |
EINECS | 0 |
Product Categories | Intermediates & Fine Chemicals;Pharmaceuticals;Steroids;APIs;Steroid and Hormone;Alrex, Lotemax;Hormone Drugs |
Chemical Properties CAS: 82034-46-6 Loteprednol etabonate
Melting point | 220.5-223.5 |
storage temp. | -20°C Freezer |
Spec.:CAS: 82034-46-6 Loteprednol etabonate
Test |
Specification | Result |
particle size (Optical microscopy) | 90%< lOmicron | Conform |
Identification | I. The infrared absorption is same as reference | Conform |
2. Max. absorption is in the wavelength 245nm | Conform | |
Individual impurity | ≤0.2% | 0.05% |
Total impurity | ≤0.5% | 0.17% |
Methanol | ≤0.3% | Not found |
Acetone | ≤0.5% | 0.11% |
Loss on drying | ≤0.5% | 0.13% |
Chlorides | ≤0.01% | <0.01% |
Heavy metals | ≤0.001 % | <0.001% |
Residue on ignition | ≤0.1% | 0.08% |
Sterility test | Should meets the requirements | Conform |
Assay (on dried base) | 98% ~ 102% | 99.6% |
Solubility :
Freely soluble in chlorofonn, insoluble in water, sparingly soluble in acetone, slightly soluble in methanol
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