Indometacin 53-86-1 Indometacin 53-86-1
Specifciation:
1.Competitive price
2.Fast Delivery Within 2 days
3.SGS , BV, GMP,ISO approve
4.Professional factory
Product Description
Certification of Analysis
Product Name |
Indomethacin |
MFG. Date |
Dec.12.2015 |
|
Batch NO. |
HS13-068 |
EXP. Date |
Dec.11.2018 |
|
Batch quantity |
300kg |
Analysis Date |
Dec.18.2015 |
|
Standard |
BP2005 |
|||
Items |
Specification |
Results |
||
Characters |
White crystalline powder ,parctically insoluble in water, sparingly soluble in alcohol |
Conforms |
||
Identification |
|
|
||
A.Melting point |
158-162°C |
158.5-160.0°C |
||
B.Absorption at 318nm |
170-190 |
185.19 |
||
C. |
Conforms to the requirement |
Conforms |
||
D. |
Conforms to the requirement |
Conforms |
||
E. |
Conforms to the requirement |
Conforms |
||
Related substances(TLC) |
Not more than 0.5% |
<0.5% |
||
Heavy metals |
Not more than 20ppm |
<20ppm |
||
Loss on drying |
Not more than 0.5% |
0.13% |
||
Sulphated Ash |
Not more than 0.1% |
0.07% |
||
Assay |
98.5%-100.5% |
99.8% |
||
Conclusion:Complies with EP7 |
Function&Application
Indometacin (INN and BAN) or indomethacin (AAN, USAN and former BAN) is a non-steroidal anti-inflammatory drug(NSAID) commonly used as a prescription medication to reduce fever, pain, stiffness, and swelling. It works by inhibiting the production of prostaglandins, molecules known to cause these symptoms.
It is marketed under more than twelve different trade names.
Clinical indications for indometacin include:
Indometacin has also been used clinically to delay premature labor, reduce amniotic fluid in polyhydramnios, and to close patent ductus arteriosus.
Indometacin is a potent drug with many serious side effects and should not be considered an analgesic for minor aches and pains or fever. The medication is better described as an anti-inflammatory, rather than an analgesic. Indometacin can also affect warfarin and subsequently raise INR.
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