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Olaparib Olaparib powder cas 763113-22-0
1.high quality:
quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed.
2.reasonable price:
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3.low moq:
no worry about the low moq, our moq is 1 gram or even lower.
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Product Name: Olaparib
Form: Powder
CAS Number: 763113-22-0
MF: C24H23FN4O3
M.W: 434.469
Brand: Salus
COA: Available
Sample: Available
Shelf Life: 2 Years
Olaparib is an inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes, including PARP1, PARP2, and PARP3. PARP enzymes are involved in normal cellular homeostasis, such as DNA transcription, cell cycle regulation, and DNA repair. Olaparib has been shown to inhibit growth of select tumor cell lines in vitro and decrease tumor growth in mouse xenograft models of human cancer both as monotherapy or following platinum-based chemotherapy.
Product Name: |
Olaparib |
MF: |
C24H23FN4O3 |
CAS No.: |
763113-22-0 |
Specification: |
99% |
Purity: |
99% |
Origin: |
China |
Item |
Specification |
Results |
Appearance |
White Powder |
White Powder |
Assay |
99.0%--101.0%(Anhydrous substance) |
99.98% |
Purity |
≥99.0% |
99.89% |
Water |
≤1.0% |
0.1% |
Sulphated ash |
≤0.5% |
0.045% |
Related substances |
Unspecified impurities for each impurity |
Complies |
Heavy Metals |
≤10ppm |
<10ppm |
Loss On Drying |
≤2.0% |
0.19% |
Microbiological Analysis |
||
Total plate count |
≤1000cfu/g |
Complies |
Yeast and moulds |
≤100cfu/g |
Complies |
E. Coli |
Negative |
Negative |
Conclusion |
Conform with specification |
Storage |
Store in sealed containers at cool & dry place. |
|
Protect from light, moisture and pest infestation. |
Shelf Life |
2 years when properly stored |
Olaparib as a maintenance therapy or monotherapy for the treatment of adult patients with recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer. On January 12, 2018, FDA expanded the approved use of Olaparib to include chemotherapy-experienced patients with germline breast cancer susceptibility gene (BRCA) mutated, human epidermal growth factor receptor 2 (HER2)-negative metastatic breast cancer.
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