Imatinib STI571; STI 571; STI-571 152459-95-5
Description:
IC50 Value: 100 nM (PDGFR) [1]; 100 nM (c-Kit) [2]
Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. Imatinib is used to treat chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies.
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Description:
IC50 Value: 100 nM (PDGFR) [1]; 100 nM (c-Kit) [2]
Imatinib is a multi-target inhibitor of v-Abl, c-Kit and PDGFR with IC50 of 0.6 μM, 0.1 μM and 0.1 μM, respectively. Imatinib is used to treat chronic myelogenous leukemia (CML), gastrointestinal stromal tumors (GISTs) and a number of other malignancies.
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