Ponatinib 943319-70-8 Ponatinib 943319-70-8
Specifciation:
1.Competitive price
2.Fast Delivery Within 2 days
3.SGS , BV, GMP,ISO approve
4.Professional factory
Description
Ponatinib (AP 24534) is a small molecule, multi-target kinase inhibitor known to potently inhibit Bcr-Abl (the fusion protein of Bcr
and c-Abl), Flk-1(VEGFR2) and FGFR. It also exhibits inhibitory activity against PDGFRα, c-Src and c-Kit. AP 24534 inhibits the
proliferation of mutant FLT3-positive cells (IC50 of 13 nM), which inhibits mutant FLT3 phosphorylation (IC50 of 1 nM) and the
proliferation of Bcr-Abl1 T315I-positive Ba/F3 cells with an IC50 of 8 nM.
Specification
Items |
Specification |
Results |
|
Appearance |
White to off-white powder |
Complies |
|
Identification |
H-NMR, MS |
Complies |
|
Loss on drying |
<1.0% |
0.35% |
|
Residue on ignition |
£0.5% |
Complies |
|
Assay(HPLC) |
Not less than 98.0% |
99.2% |
|
Conclusion:The above substance has been tested according to In-house Standard, and it meets requirements. |
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A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q7:How do you treat quality complaint
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.
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