Details:
Hydrafinil Basic Info:
Name : 9-Hydroxyfluorene
Synonyms : 9H-Fluoren-9-ol
CAS :1689-64-1
Molecular Formula: C13H10O
Molecular Weight:182.22
EINECS: 216-879-0
MP: 153-154 °C(lit.
Other name:TIMTEC-BBSBB007717;9h-fluoren-9-ol;DIPHENYLENECARBINOL;9-HYDROXY- FLUOREN:
9-HYDROXYFLUORENE; 9-FLUORENOL; Hydroxyfluoren;fluoren-9-ol
Hydrafinil Specification:
1 .Appearance : White to off-white crystalline powder or lumps
2 .Specific Optical Rotation (c=0.5,10% HAc) :-50.0~-60.0°
3 .Water Content(Karl Fischer) : ≤5.0%
4 .Acetate Content(by HPLC) : ≤15.0%
5 .Amino Acid Composition : ±10% of theoretical
6 .Purity (by HPLC) :≥98.0%
7 .Single Impurity(by HPLC) :≤1.0%
8 .Peptide Content(by %N) : ≥80%
9 .Assay(By Anhydrous, Acetic Acid-free ) :95.0~105.0%
10 .Bacterial Endotoxins : ≤5EU/mg
What is Hydrafinil
Fluorenol is an alcohol derivative of fluorene. In the most significant isomer, fluoren-9-ol or 9-hydroxyfluorene, the hydroxy group is located on the bridging carbon between the two benzene rings. Hydroxyfluorene can be converted to fluorenone by oxidation. It is a white-cream colored solid at room temperature.
Fluorenol is an alcohol derivative of fluorene and is being clasisfied as a eugeroic compound, promoting wakefulness. The company Cephalon investigated Fluorenol in comparison to the popular eugeroic drug modafinil. In their comparison research with rodents, they noted that Fluorenol was significantly more effective than modafinil (up to 39%). Although it has dopamine reuptake properties, they tend to be pretty weak.
Hydrafinil Benefit:
Dopamine reuptake inhibitor: An increase in dopamine production is known to improve cognition. Hydrafinil plays a role as a dopamine reuptake inhibitor, increasing dopamine concentrations.
5-HT6 antagonist: Antagonism of 5-HT6 receptor can result to increase in norepinephrine and dopamine concentrations in the prefrontal cortex, as well as increasing the production of choline and glutamate in different parts of the brain. Makers of Hydrafinil theorize that it functions as a 5-HT6 receptor antagonist.
Increase Glutamate levels: As mentioned earlier, antagonism of 5-HT6 receptors increases the production of glutamate in the brain. This could lead to enhanced memory and learning process. There is a great possibility that Hydrafinil's function as a 5-HT6 receptor antagonist could result in the improvement of cognitive performance.
Increase Norepinephrine levels: Manufacturers of Hydrafinil claim that it increases norepinephrine levels specifically in the prefrontal cortex by antagonizing 5-HT6 receptor. Increase in concentrations of norepinephrine could result to improvement of cognition. However, there's no enough evidence to prove this theory.
Increase Histamine levels: Hydrafinil is known to enhance histamine levels in the hypothalamus. Histamine plays an important role in normalizing our circadian rhythm and regulating sleep-wake cycles.
Hydrafinil Function & Application:
Used in medicine, health products, food, beverage, cosmetics, biological and chemical reagents and other industries.This drug hasn’t been involved in any human clinicial testing or trials therefore a safe dosage and any potential side effects have not been established.
Custom clearance service:
1) By Express:
Normally there is no specical need for the recipient to clear the customs. If the customs has an objection,our rich experienced and peofessional group will help you clear the customs. We can guarantee th shipment 100%.
2) By Air and by Sea:
Our company will cooperate with the recipient to provide relevant file and information in the customs clearance procedure.
Delivery Service:
We can ship out within 5 days after you make payment if it have stock at Lab, We always send all order by DHL, UPS, TNT, FedEx, EMS and other courier with door-door service, take 5 – 7 business days to your door!
Packing:
Carton: 1kg, 2kg, 5kg with Foil bag inside, or as customer's requirment;
Drum: 10kg, 15kg, 25kg with food grade PE nag inside.
Delivery:
Shipping Terms |
By Express |
By Air |
By sea |
Suitable for ≤ 50kg
Faster 5-7days
High Cost
Door to Door
Easy Pick Up Goods
|
Suitable for ≥ 50kg
Fastest: 1-2 days
High Cost
Airport to Airport
Pick Up Goods by Customer
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Suitable for ≥ 500kg
Fast: 15-30 days
Low Cost
Port to Port
Pick Up Goods by Customer
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Payment:
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Q1: Can i get some samples
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, or Paypal or Escrow(Alibaba).
Q3: How to confirm the Product Quality before placing orders
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4:What’s your MOQ
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5: How about delivery leadtime
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6:Is there a discount
A:Different quantity has different discount.
Q7: How do you treat quality complaint
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.