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Details:
PQQ (Pyrroloquinoline Quinone) Basic Info:
PQQ Pyrroloquinoline Quinone
CAS : 122628-50-6
Formula C14H6N2O8
Synonyms:PQQ, Methoxatin, Pyrroloquinoline, Pyrroloquinoline quinone
Appearance: Dark red powder
Density 1.963 g/cm3
Boiling Point 1018.6 °C at 760 mmHg
Molecular Weight 330.21
Flash Point 569.8 °C
Specification Available: 99% HPLC
[Specs] NLT 99%, Food Grade, Pharmaceutical Grade
Item |
Specifications |
Results |
Assay(HPLC) |
98.0%~102.0% |
98.9% |
Appearance |
Dark Red fine powder |
Complies |
Identification |
IR |
Complies |
Melting point |
156.0~160.0℃ |
157.0~158.0℃ |
Loss on drying |
≤0.5% |
0.11% |
Residue on ignition |
≤0.1% |
0.06% |
Related substance |
≤1.0% |
0.75% |
Heavy metals |
≤10ppm |
Complies |
Real Point:
What is PQQ (Pyrroloquinoline Quinone)
Pyrroloquinoline quinone (henceforth PQQ) is a small quinone molecule which has the ability to be a REDOX agent, capable of reducing oxidants (an antioxidant effect) and then being recycled by glutathione back into an active form. It appears to be quite stable as it can undergo several thousand cycles before being used up, and it is novel since it associates with protein structures inside the cell (some antioxidants, mostly notably carotenoids like β-carotene andAstaxanthin, are located at specific areas of a cell where they exert proportionally more antioxidant effects due to proximity; PQQ seems to do this near proteins like carotenoids do so at the cell membrane).
The aforementioned REDOX functions can alter protein function and signalling pathways, and while there is a lot of promising in vitro (outside of a living model) research on what it could do there are only a few promising results of PQQ supplementation, mostly related to either altering some signalling pathways or via its benefits to mitochondria (producing more of them and increasing their efficiency).
It is a coenzyme in bacteria (so, to bacteria, this would be something like a B-vitamin) but this role does not appear to extend to humans. Since this does not extend to humans, the designation of PQQ as a vitamin compound has fallen through and it is only considered 'vitamin-like' at best.
PQQ (Pyrroloquinoline Quinone) Benefit:
Much of the research concerning the therapeutic properties of PQQ has been conducted in animals, however and it is not clear yet whether these benefits can be extrapolated to humans. There are however a select number of recent studies in humans, which suggest that some of the benefits seen in animal studies may also transfer to humans.
Increased Growth Rate
Studies in rats and mice show that when added to nutritionally complete, semi-purified diets devoid of PQQ, as little as 300 ug PQQ per kg diet improves reproduction and enhances neonatal rates of growth compared to diets devoid of PQQ.
Antioxidant
The reduced form of PQQ used in supplements has been proven to be a potent antioxidant that is relatively stable and therefore more efficient in its action compared with other endogenous antioxidants.
Anti-Inflammatory
In one of the few oral supplementation studies in humans with PQQ, it was shown to dramatically reduce the levels of c-reactive protein (CRP); one of the most reliable indicatorsof inflammation1. Raised inflammation is related to a wide range of chronic diseases and as such, any nutrient or agent that can reduce inflammation is generally beneficial to a range of health outcomes.
Fat Oxidation
Studies in animals and humans show PQQ has the potential to improve a process called beta-oxidation, which is the bodys main pathway for generating energy from fat5, 6. This is also the area where PQQ may possibly improve performance in athletes.
Anabolic
There is also data in human and animal studies showing supplementation with PQQ may improve nitrogen retention in muscle and therefore have anabolic properties with regard to muscle growth.
PQQ (Pyrroloquinoline Quinone) Function & Application:
1.Improve the body's immune function
As a necessary factor of human development, it can stimulate the growth of cells in the body, especially the activation of human B cells, T cells, antibody production, improve the immune function of human body.Pyrroloquinoline Quinone is the most powerful bioactive substances so far.
2. Prevent and treat the liver damage
Can significantly reduce serum bilirubin, alanine aminotransferase levels, make liver function normal, regulate liver damage and have very good curative effect on liver disease.
3. Reduce free radical damage to human body
PQQ is a kind of oxidoreductase prosthetic group, involved in biological REDOX reaction in the body, can effectively remove free radicals in the body, reduce the harm of human body free radical, protect tissues, reduce the body damage caused by various diseases, such as heart disease, cancer and all kinds of inflammation.Free radicals is the source of diseases.
4. Regulate various neurological diseases
Pyrroloquinoline Quinone is a new kind of water-soluble vitamins, can promote the synthesis of neural factors in the human body, regulate various neurological diseases.
5. Promote the absorption of amino acids
Pyrroloquinoline Quinone is the prosthetic group of quinone protease, participate in the respiratory electron transport chain, in the human body through the effect of glucose, can promote the absorption of amino acids.Amino acid composition of cell SAP and synthetic protein peptide is the main raw material, is an important part of the body's biological active substances.
6. Promote the synthesis of growth factors
Growth factor is the human growth hormone, stimulate biological growth, can stimulate human body cell growth, increase the cell density.Trace amounts of Pyrroloquinoline Quinone could improve the biological function of the organization's ability to metabolize and growth.Why can slow the aging
7.Prevent and treat the alzheimer's disease
Pyrroloquinoline Quinone special biological activity and physiological function but also has the repair nerve fibers, the activation of neurons, activate the dormancy of the nerve cells, can effective prevention and treatment of alzheimer's disease and improve memory.Can effectively improve intelligence.
8.Promote the synthesis of glutathione
Glutathione by glutamic acid, cysteine and glycine combination of three peptides, has an important antioxidant effect, integrating detoxification, harmful to the body poison into harmless substance, excreted in vitro, glutathione is bioactive enhancer.Pyrroloquinoline Quinone can promote the body's glutathione synthesis, prevent and accumulation of hepatic bilirubin in cataract.
PQQ (Pyrroloquinoline Quinone) Dosage:
A suitable dose for enhancing mitochondria is 0.075 to 0.3mg/kg daily
About 20 mg is capable of decreasing inflammation for an average-weight male
I recommend to take it every other day or daily if you are trying to correct a problem
Custom clearance service:
1) By Express:
Normally there is no specical need for the recipient to clear the customs. If the customs has an objection,our rich experienced and peofessional group will help you clear the customs. We can guarantee th shipment 100%.
2) By Air and by Sea:
Our company will cooperate with the recipient to provide relevant file and information in the customs clearance procedure.
Delivery Service:
We can ship out within 5 days after you make payment if it have stock at Lab, We always send all order by DHL, UPS, TNT, FedEx, EMS and other courier with door-door service, take 5 – 7 business days to your door!
Packing:
Carton: 1kg, 2kg, 5kg with Foil bag inside, or as customer's requirment;
Drum: 10kg, 15kg, 25kg with food grade PE nag inside.
Delivery:
Shipping Terms |
By Express |
By Air |
By sea |
Suitable for ≤ 50kg
Faster 5-7days
High Cost
Door to Door
Easy Pick Up Goods
|
Suitable for ≥ 50kg
Fastest: 1-2 days
High Cost
Airport to Airport
Pick Up Goods by Customer
|
Suitable for ≥ 500kg
Fast: 15-30 days
Low Cost
Port to Port
Pick Up Goods by Customer
|
Payment:
Payment terms |
Western Union |
Moneygram |
PayPal |
Wire Transfer |
Bitcoin |
Q1: Can i get some samples
A: Yes, we can supply the free sample, but the shipping cost be paid by our customers.
Q2: How to start orders or make payments
A: Proforma invoice will be sent first after confirmation of order, enclosed our bank information. Payment by T/T, or Paypal or Escrow(Alibaba).
Q3: How to confirm the Product Quality before placing orders
A:You can get free samples for some products,you only need to pay the shipping cost or arrange a courier to us and take the samples. You can send us your product specifications and requests,we will manufacture the products according to your requests.
Q4:What’s your MOQ
A:Our MOQ is 1kg. But usually we accept less quantity such as 100g on the condition that sample charge is 100% paid.
Q5: How about delivery leadtime
A:Delivery lead time: About 3-5 days after payment confirmed. (Chinese holiday not included)
Q6:Is there a discount
A:Different quantity has different discount.
Q7: How do you treat quality complaint
A:First of all, our quality control will reduce the quality problem to near zero. If there is a real quality problem caused by us, we will send you free goods for replacement or refund your loss.