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Factory Supply High Purity API Entecavir hydrate

Factory Supply High Purity API Entecavir hydrate

Min.Order / FOB Price:Get Latest Price

10 Gram

Negotiable

  • Min.Order :10 Gram
  • Purity: 99%
  • Payment Terms : T/T,

Keywords

Entecavir hydrate Entecavir cas 209216-23-9

Quick Details

  • Appearance:white powder
  • Application:the treatment of adult chronic hepatitis b in which there is active viral replication, increased serum transaminase ALT or active lesions showed from liver histology.
  • PackAge:aluminum foil bag
  • ProductionCapacity:100|Kilogram|Month
  • Storage:cool and dry place
  • Transportation:email: wonda-chem@outlook.com

Superiority:

1.high quality:

quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed.

2.reasonable price:

we provide high quality products with competitive price in china. all customers are welcomed to send us inquiries and get quotation.

3.low moq:

no worry about the low moq, our moq is 1 gram or even lower.

4.good service.

fast response. we promise to reply within 24 hours including holidays and send quotation sheet and other documents within 48 hours.

5. fast shipping and secure courier.

we promise to send out products and provide tracking number within 3 working days. and we send via different couriers based on different destination countries. we usually use nl post, hk post, germany post, eub, etk, etc.

 

Details:

Description

 

Product Name
Entecavir hydrate
Synonyms
entecavir hydrate;ENTECAVIR MONOHYDRATE;2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate;Entecavir hydrate / 2-Amino-1,9-dihydro-9-[(1S,3R,4S)-4-hydroxy-3-(hydroxymethyl)-2-methylenecyclopentyl]-6H-purin-6-one monohydrate;
CAS
209216-23-9
MF
C12H17N5O4
MW
295.29448

 

Introduction

  

Entecavir hydrate is a new kind of cyclopentyl acyl guanosine anti-hepatitis b virus drugs with its pharmacological effects similar as entecavir. It is clinically applied to the treatment of adult chronic hepatitis b in which there is active viral replication, increased serum transaminase ALT or active lesions showed from liver histology. 
This product is a kind of analogues of guanine nucleoside which has inhibitory on the polymerase of hepatitis b virus (HBV). It can become active triphosphate salts through phosphorylation. The triphosphate salt has a half-life of 15 hours inside a cell. Through completion with the natural substrates of HBV polymerase, guanine nucleoside triphosphate, entecavir triphosphate can suppress all the three types of activities of the virus polymerase (reverse transcriptase): 
(1) The initiation of HBV polymerase.
(2) The formation of the negative chain of reverse transcription of the pre-genome.
(3) The synthesis of HBVDNA positive chain.

 

 

 

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