Bosentan Hydrate Bosentan hydrate powder cas 157212-55-0
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Product Description
English name: Bosentan hydrate
Synonyms:Benzenesulfonamide,4-(1,1-dimethylethyl)-N-[6-(2-hydroxyethoxy)-5-(2-methoxyphenoxy)[2,2'-bipyrimidin]-4-yl]-,monohydrate (9CI)
Specification: 98%
CAS NO.:157212-55-0
Appearance: white crystalline powder
Molecular weight: 569.63
Molecular formula:C27H31N5O7S
Product name |
Bosentan hydrate |
CAS NO. |
157212-55-0 |
Synonyms |
Bosentan hydrate |
Category | Pharmaceutical Raw Materials,Active Pharmaceutical Ingredients,Bulk Drugs,Fine Chemicals. |
Purity |
99% Bosentan hydrate |
Appearance |
Bosentan hydrate powder |
Shelf life | 2 years for Bosentan hydrate |
Usage |
Bosentan hydrate is used in the treatment of pulmonary artery hypertension (PAH). |
Storage | Bosentan hydrate should be stored in a well-closed container at low temperature, keep away from moisture, heat and light. |
Specification
Items |
Specifications |
Results |
Appearance |
White to yellowish powder |
Off-white powder |
Identification |
IR HPLC |
Conforms |
Water |
2.0 -4.0% |
3.00% |
Related Substance
|
Impurity A ≤ 0.2% Impurity B ≤ 0.2% Impurity C ≤ 0.2% Other indidual impurity ≤ 0.2% Total impurity: ≤ 1.0% |
Not detected 0.17% 0.14% 0.02% 0.37% |
Heavy metals |
≤ 20 ppm |
Complies |
Residual solvents |
Ethanol: ≤ 0.2% Toluene: ≤ 0.089% Methanol: ≤ 0.02% |
Complies |
Residue on ignition |
≤ 0.1% |
0.05 %w/w |
Assay(on drying basis) |
99% |
99.5% |
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