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china tianeptine acid manufacturers china 30123-17-2 factory 30123-17-2
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1.Tianeptine Sodium
2.Specification: 99%
3.CAS 30123-17-2
4.Appearance:White crystalline powder
5.GMP BV SGS ISO
Description of Tianeptine Sodium
Tianeptine is a drug used primarily in the treatment of major depressive disorder, although it may also be used to treat asthma or irritable bowel syndrome. Chemically it is a tricyclic antidepressant (TCA), but it has different pharmacological properties than typical TCAs as recent research suggests that tianeptine produces its antidepressant effects through indirect alteration of glutamate receptor activity (i.e., AMPA receptors and NMDA receptors) and release of BDNF, in turn affecting neural plasticity.
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Tianeptine sodium salt Chemical Properties |
Melting point | 1800C |
storage temp. | Desiccate at RT |
solubility | DMSO: ≥20mg/mL |
form | solid |
color | white to tan |
Merck | 14,9420 |
CAS DataBase Reference | 30123-17-2(CAS DataBase Reference) |
Safety Information |
WGK Germany | 3 |
MSDS Information |
Provider | Language |
---|---|
SigmaAldrich | English |
Tianeptine sodium salt Usage And Synthesis |
Chemical Properties | White to Yellowish Powder |
Uses | Tricyclic compound with psychostimulant, anti-ulcer and anti-emetic properties. Antidepressant |
Uses | Tianeptine (INN) (Stablon, Coaxil, Tatinol) is a selective serotonin reuptake enhancer (SSRE) drug used for treating major depressive episodes (mild, moderate, or severe). Unlike conventional tricyclic antidepressants, tianeptine enhances the reuptake of |
Biological Activity | Selective facilitator of 5-HT uptake in vitro and in vivo . Has no affinity for a wide range of receptors, including 5-HT and dopamine (IC 50 > 10 μ M) and has no effect on noradrenalin or dopamine uptake. Antidepressant, analgesic and neuroprotective following systemic administration in vivo . |
CAS NO:30123-17-2
CAS NO:30123-17-2
CAS NO:30123-17-2
CAS NO:30123-17-2
CAS NO:30123-17-2
CAS NO:30123-17-2
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