Factory Price Good Quality Sunitinib Malate CAS 341031-54-7

Factory Price Good Quality Sunitinib Malate CAS 341031-54-7

Basic Info.

Name:Sunitinib Malate
Synonym: Malic acid Shu;N-[2-(Diethylamino)ethyl]-5-[(Z)-(5-fluoro-1,2-dihydro-2-oxo-3H-indol-3-ylidene)methyl]-2,4-dimethyl-1H-pyrrole-3-carboxamide (2S)-2-hydroxybutanedioic acid (1:1) salt
CAS No.:341031-54-7
Molecular formula: C22H27FN4O2.C4H6O5
Molecular weight:532.566
Melting point: 189-191°C
Appearance: light crystalline powder 



Function

Sunitinib malate is used to treat the renal cell carcinoma and imatinib-resistant gastrointestinal stromal tumor.

Package & Storage:
Sunitinib malate is packed in 1kg in a Al foil bag&25kg/barrel. The packaging can be customised;
Sunitinib malate Powderis stored in a cool and dry well-closed container, the temperature should be lower than 25° C, the relative humidity should not exceed 50%.



Usage

Sunitinib malate is an oral, small-molecule, multi-targeted receptor tyrosine kinase (RTK) inhibitor that was approved by the FDA for the treatment of renal cell carcinoma (RCC) and imatinib-resistant gastrointestinal stromal tumor (GIST) on January 26, 2006. Sunitinib was the first cancer drug simultaneously approved for two different indications.

Sunitinib inhibits cellular signaling by targeting multiple receptor tyrosine kinases (RTKs).

These include all receptors for platelet-derived (PDGF-Rs) and vascular endothelial  receptors (VEGFRs), which play a role in both tumor angiogenesis and tumor cell proliferation.