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Alfacalcidol the intermediates of Alfacalcidol Calcitriol analogue
Alfacalcidol is an analogue of calcitriol that only needs to be hydroxylated in the liver to become active 1, 25- (0H) 2D3.This product can increase the small intestine and renal tubules to calcium reabsorption, inhibit parathyroid hyperplasia, reduce parathyroid hormone synthesis and release, inhibit bone absorption;Increased the synthesis of transforming growth factor-b (TGF -- B) and insulin-like growth factor-i (1GF -- I), and promoted the synthesis of collagen and bone matrix proteins.Regulate muscle calcium metabolism, promote muscle cell differentiation, enhance muscle strength, increase neuromuscular coordination, and reduce falling tendency.
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