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Calcitriol the intermediates of Calcitriol Calcitriol
Calcitriol is the most active 1, 25-dihydroxyl metabolite of vitamin D3 metabolized by hydroxylase in liver and kidney to prevent rickets.Can promote the absorption of intestinal calcium;Can stimulate the original osteoclast activity or accelerate the formation of new osteoclasts, so as to promote the absorption of bone, calcium and phosphorus in the blood transfer of human blood circulation;Promote the absorption of calcium and phosphorus in the proximal convoluted tubule of the kidney, and increase the concentration of blood calcium and phosphorus.After oral administration, it is rapidly absorbed from the small intestine without metabolic activation and partially degraded by the kidneys.
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