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Polysorbate 20; Tween 20 Polisorbate 20- PS 20;Tween 20 (Trademark of ICI America, Inc.);Tween 20 ;Tween 20 1LT;Twain 20;TWEEN(R) 20 Vetec(TM) reagent grade, 40%;Tween 20 Tween 20 1LT;Polysprbate21 detergent;Ester Ether Type (Surfactants);#N/A;Functional Materials;Nonionic Surfactants;Surfactants;Biochemistry;
Polysorbate 20 Basic information |
Product Name: | Polysorbate 20 |
Synonyms: | Polisorbate 20- PS 20;Tween 20 (Trademark of ICI America, Inc.);Tween 20 ;Tween 20 1LT;Twain 20;TWEEN(R) 20 Vetec(TM) reagent grade, 40%;Tween 20 Tween 20 1LT;Polysprbate21 |
CAS: | 9005-64-5 |
MF: | C26H50O10 |
MW: | 522.6692 |
EINECS: | 500-018-3 |
Product Categories: | -;detergent;Ester Ether Type (Surfactants);#N/A;Functional Materials;Nonionic Surfactants;Surfactants;Biochemistry;Nonionic Surfactants (for Biochemistry);Surfactants (for Biochemistry);Alphabetical Listings;Flavors and Fragrances;O-P |
Mol File: | 9005-64-5.mol |
|
Polysorbate 20 Chemical Properties |
Boiling point | 100 °C |
density | 1.11 g/mL at 20 °C |
vapor pressure | <1.4 hPa (20 °C) |
FEMA | 2915 | POLYSORBATE 20 |
refractive index |
n |
Fp | >230 °F |
storage temp. | 0-6°C |
solubility | 100 g/L |
form | viscous liquid |
Specific Gravity | 1.090~1.130 (20/20℃) |
color | Amber |
PH | 6-8 (50g/l, H2O, 20℃) |
Water Solubility | 100 g/L |
Hydrophilic-Lipophilic Balance (HLB) | 16.7 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
EPA Substance Registry System | Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivs.(9005-64-5) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 22-36/37/38-37/38-41 |
Safety Statements | 24/25-36/37/39-36-26 |
WGK Germany | 1 |
RTECS | TR7400000 |
F | 10-23 |
TSCA | Yes |
HS Code | 34021300 |
Toxicity | LD50 orally in Rabbit: 38900 mg/kg |
Polysorbate 20 Usage And Synthesis |
Description |
Tween 20, whose common commercial names includes Alkest TW 20 and Polysorbate 20, is a mild nonionic surfactant formed by the ethoxylation of sorbitan before the addition of lauric acid which is a medium-chain fatty acid found mainly in coconut oil. It is allowed to be used as the emulsifier, detergent, dispersant, solvent and stabilizer, etc. in a number of fields such as pharmaceutical, chemical, food, textile and other industries due to its stability and relative non-toxicity. Tween 20 is widely applied in biological techniques and sciences, which can be added to buffers and reagents for immunohistochemistry, such as Western blots and ELISAs, helping to prevent non-specific antibody binding, decrease background staining and enhance reagent spreading. Besides, Tween 20 also has applications in food production as a common food grade additive which are found in many consumables on the market today. It can also be used as a wetting agent in flavored mouth drops such as Ice Drops, in oral or non-gastrointestinal suspensions and in rubber balers in the elastomer industry. |
References |
#; # |
Chemical Properties | Yellow liquid |
Uses | Pharmaceutic aid (surfactant). |
Uses | polysorbate 20 is a solubilizer, emulsifier, viscosity modifier, and stabilizer of essential oils in water. |
Definition | ChEBI: A polymer composed of PEG-ylated sorbitan, where the total number of poly(ethylene glycol) units is 20 (w + x + y + z = 20) and a single terminal is capped by a dodecanoyl group. |
Brand name | Tween 20 (ICI Americas). |
Safety Profile | Moderately toxic by intravenous route. Mddly toxic by ingestion. A human skin irritant. When heated to decomposition it emits acrid smoke and irritating fumes. |
Polysorbate 20 Preparation Products And Raw materials |
Raw materials | ETHYLENE OXIDE-->Sodium ethoxide |
Polysorbate 20 Basic information |
Product Name: | Polysorbate 20 |
Synonyms: | Polisorbate 20- PS 20;Tween 20 (Trademark of ICI America, Inc.);Tween 20 ;Tween 20 1LT;Twain 20;TWEEN(R) 20 Vetec(TM) reagent grade, 40%;Tween 20 Tween 20 1LT;Polysprbate21 |
CAS: | 9005-64-5 |
MF: | C26H50O10 |
MW: | 522.6692 |
EINECS: | 500-018-3 |
Product Categories: | -;detergent;Ester Ether Type (Surfactants);#N/A;Functional Materials;Nonionic Surfactants;Surfactants;Biochemistry;Nonionic Surfactants (for Biochemistry);Surfactants (for Biochemistry);Alphabetical Listings;Flavors and Fragrances;O-P |
Mol File: | 9005-64-5.mol |
|
Polysorbate 20 Chemical Properties |
Boiling point | 100 °C |
density | 1.11 g/mL at 20 °C |
vapor pressure | <1.4 hPa (20 °C) |
FEMA | 2915 | POLYSORBATE 20 |
refractive index |
n |
Fp | >230 °F |
storage temp. | 0-6°C |
solubility | 100 g/L |
form | viscous liquid |
Specific Gravity | 1.090~1.130 (20/20℃) |
color | Amber |
PH | 6-8 (50g/l, H2O, 20℃) |
Water Solubility | 100 g/L |
Hydrophilic-Lipophilic Balance (HLB) | 16.7 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
EPA Substance Registry System | Sorbitan, monododecanoate, poly(oxy-1,2-ethanediyl) derivs.(9005-64-5) |
Safety Information |
Hazard Codes | Xi |
Risk Statements | 22-36/37/38-37/38-41 |
Safety Statements | 24/25-36/37/39-36-26 |
WGK Germany | 1 |
RTECS | TR7400000 |
F | 10-23 |
TSCA | Yes |
HS Code | 34021300 |
Toxicity | LD50 orally in Rabbit: 38900 mg/kg |
Coreychem |
Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.
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At present, in addition to our headquarters in Zhengzhou, we also have another product base in Jun County, Henan Province. This base is the attracting investment of science and technology project of Jun County govenment’s, which covers 6529 square meters. In addition to bear our own company’s 1000L-5000L pilot task, also bear the function of Henan pilot incubation service platform, In order to improve Henan and surroundings’ synthetic reaction pilot service ability and the key technology development capabilities. Base with three GMP standards workshop, a testing center, one test center,one experiment center and associatd supporting facilities, can carry out oxidation, hydrogenation (70 kg pressure), halogenated, acieration, etherification, condensation, cyclization, formatting, ammoniated, diazotization andpilot service such as azide reactions etc. In the future we will work hard to make it become the most complete production system in central China and even the whole country, the highest technical level, the strongest talent team, the most popular service scope of pilot incubation service platform.
Henan Coreychem co., LTD. is committed to provide cost effective chemical service to the global fine chemical industry product development agencies; we adhering to the consistent good commercial reputation, to create a highly efficient, high quality of chemical research, development, production, sales and service of integrated platform, let our customers faster, better get ideal and thoughtful service.
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