Good Price/Top Qual...

Good Price/Top Quality 99.0%, Ezetimibe Powder

Good Price/Top Quality 99.0%, Ezetimibe Powder

Min.Order / FOB Price:Get Latest Price

10 Gram

Negotiable

  • Min.Order :10 Gram
  • Purity: 99%
  • Payment Terms : T/T,

Keywords

Ezetimibe Powder Ezetimibe CAS 163222-33-1

Quick Details

  • Appearance:white powder
  • Application:Ezetimibe is a kind of new selective cholesterol absorption inhibitor, with small intestinal brush border membrane vesicles on membrane protein (molecular weight 145X103) binding, inhibition of small
  • PackAge:aluminum foil bag
  • ProductionCapacity:100|Kilogram|Month
  • Storage:cool and dry place
  • Transportation:email: wonda-chem@outlook.com

Superiority:

1.high quality:

quality is life. quality is the most important element for all goods. we have a lab doing research in wuhan china. hplc and nmr is available if needed.

2.reasonable price:

we provide high quality products with competitive price in china. all customers are welcomed to send us inquiries and get quotation.

3.low moq:

no worry about the low moq, our moq is 1 gram or even lower.

4.good service.

fast response. we promise to reply within 24 hours including holidays and send quotation sheet and other documents within 48 hours.

5. fast shipping and secure courier.

we promise to send out products and provide tracking number within 3 working days. and we send via different couriers based on different destination countries. we usually use nl post, hk post, germany post, eub, etk, etc.

 

Details:

Product name: Ezetimibe

Other name:   Ezetimide 

Specification:   99%

CAS :    163222-33-1 
Color :  white or off white powder
Molecular formula: CC24H21F2NO3
MW   409.43
Grade :  Pharmaceutical grade
Assay:  99% by HPLC

 

  Ezetimibe is a kind of new selective cholesterol absorption inhibitor, with small intestinal brush border membrane vesicles on membrane protein (molecular weight 145X103) binding, inhibition of small intestine on diet and transported to the intestinal cholesterol absorption via the bile, reduce cholesterol content in serum and liver

Specification:

Item Specifications Results
Appearance White to off-white powder Complies
Identification A. IR : Similar to Reference Substance Complies
B. Meets the requirement Complies
Specific Rotation -25°~ -30° -27°
Water Not more than 0.5% 0.10%
Any single other impurity Not more than 0.1% 0.03%
Total impurities Not more than 1.0% 0.10%
Assay 98.5%~102.0% 99.80%
Conclusion The results conforms with enterprise standards

Function:

Ezetimibe is a new class of selective cholesterol absorption inhibitors that inhibits the delivery of small intestine to the diet and bile to the intestine by binding to the small vesicle membrane protein (relative molecular mass 145X103) in the small intestine brush border membrane. The absorption of cholesterol lowers the cholesterol content in serum and liver. Unlike bile acid chelating agents, ezetimibe does not affect the absorption of cholesterol esters, other terpenoids (such as taurocholic acid), triacylglycerols, and fat-soluble vitamins. Its pharmacological action is independent of the inhibition of acetyl-CoA cholesterol acetyltransferase (ACAT) and the expression of LDL receptor (scavenger receptor). After being absorbed, ezetimibe is bound to glucuronic acid in the liver and then circulated through the liver and intestine, and is almost exclusively localized to small intestinal mucosal cells.

 

 

 

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