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100 Gram |
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Polyquaternium-1 PQ-1 Polidronium Chloride
Amber to dark brown solid, fairly hygroscopic; bland in taste and nonirritating. Have a large solubility in water, insoluble in ethanol, acetone or ethyl ether.
No obvious stimulation to the skin, not skin sensitization agent and revulsant, has good antibacterial properties; can be used as antiseptic for eye-drops.Ophthalmic preservative Polyquaternium-1 (PQ-1), are critical for the inhibition of growth of microbial contaminants in multi-dose bottles of topical medications.
Items |
Standard |
Results |
Appearance |
Light yellow to Agate crystal powder |
Conform |
Odor |
Without Stimulation |
Conform |
Water solubility |
100% Soluble |
Conform |
Free Amin |
≤2.0% |
1.5% |
Residue on Ignition |
≤0.2% |
<0.2% |
Heavy Metals |
≤20 ppm |
<20 ppm |
pH |
6.0~9.0 |
6.90 |
Chloride |
≤25% |
Conform |
Solid Content |
≥95% |
Conform |
Assay |
95~100% |
Conform |
Total Aerobic Bacteria |
≤100 cfu/g |
Conform |
Fungi/Yeast |
≤10 cfu/g |
Conform |
Enterobacteria in 1g |
Negative |
Negative |
Pseudomonas Aeruginosa in 1g |
Negative |
Negative |
Staphylococcus Aureus in 1g |
Negative |
Negative |
Amber to dark brown solid, fairly hygroscopic; bland in taste and nonirritating. Have a large solubility in water, insoluble in ethanol, acetone or ethyl ether.
No obvious stimulation to the skin, not skin sensitization agent and revulsant, has good antibacterial properties; can be used as antiseptic for eye-drops.
Ophthalmic preservative, Polyquaternium-1 (PQ-1), are critical for the inhibition of growth of microbial contaminants in multi-dose bottles of topical medications.
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