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Prevention and treatment of acute enteritis 98% purity Best Prices
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Brief Introduction:
Product Name: | Somatostatin Acetate |
CAS NO.: | 38916-34-6 |
Molecular Formula: | C76H104N18O19S2 |
Molecular Weight: | 1637.88 |
Purity(HPLC): | 98.0%min. |
Single Impurity (HPLC): | 1.0%max |
Amino Acid Composition: | ±10% of theoretical |
Peptide Content (N%): | >=80.0% |
Water Content (Karl Fischer): | ≤8.0% |
Mass Balance : | 95.0~105.0% |
Acetate Content (HPIC) : | <=15.0% |
MS(ESI): | Consistent |
Assay(By Anhydrous, Acetic Acid-free): | -37.0~-47.0°(c=1 1%HAc) |
Storage: | Closed, below 2 ~ 8ºC preservation |
Grade: | Pharmaceutical Grade |
Apperance: | White powder |
1. Somatostatin has two active forms produced by alternative cleavage of a single preproprotein: one of 14 amino acids, the other of 28 amino acids.
2. In all vertebrates, there exist six different somatostatin genes that have been named SS1, SS2, SS3, SS4, SS5, and SS6. The six different genes along with the five different somatostatin receptors allows somatostatin to possess a large range of functions. Humans have only one somatostatin gene, SST.
Applications:
Mainly has a strong angiotensin II vasoconstriction and increase in blood pressure. The mechanism is: 1. So that the body arteriole smooth muscle contraction, increased peripheral resistance; 2. So increase the release of adrenal aldosterone, causing sodium retention, increased blood volume; 3. Directly contribute to renal tubular sodium and water reabsorption; 4. So the brain central nervous sympathetic vasoconstrictor activity, causing increased peripheral vascular resistance; 5. Stimulate the adrenal medulla to release and nor.
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