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Medicine / Food Grade L-Menthol CAS: 2216-51-5 Healty Food Addictives
Description:
Menthol is an organic compound made synthetically or obtained from corn mint, peppermint, or other mint oils. It is a waxy, crystalline substance, clear or white in color, which is solid at room temperature and melts slightly above.
The main form of menthol occurring in nature is (−)-menthol, which is assigned the (1R,2S,5R) configuration. Menthol has local anesthetic and counterirritant qualities, and it is widely used to relieve minor throat irritation. Menthol also acts as a weak kappa opioid receptor agonist.
Basic Information:
CAS No: 2216-51-5
Chemical Name: L-Menthol
Other names: 1-Menthol; (1R,3R,4S)-(-)-menthol; (-)Menthol; Levomenthol; Cyclohexanol, 5-methyl-2-(1-methylethyl)-, [1R-(1α,2β,5α)]-; L-(-)-Menthol; Menthol, (1R,3R,4S)-(-)-; (R)-(-)-Menthol; U.S.P. Menthol; 1R-Menthol; (1R,2S,5R)-(-)-Menthol; (-)-Menthyl alcohol; (1R-(1-α,2-β,5-α))-5-Methyl-2-(1-methylethyl)cyclohexanol; (1R)-(-)-Menthol; (1R,2S,5R)-2-Isopropyl-5-methylcyclohexanol; Cyclohexanol, 5-methyl-2-(1-methylethyl)-, (1R,2S,5R)-; NSC 62788CBNumber: CB7390694
Molecular Formula: C10H20O
Formula Weight: 156.27
Melting point:41-44 °C(lit.)
alpha -51 º (589nm, c=10, EtOH)
Boiling point:212 °C(lit.)
Density 0.89 g/mL at 25 °C(lit.)
vapor pressure 0.8 mm Hg ( 20 °C)
refractive index 1.46
FEMA 2665
Flash point:200 °F
storage temp. −20°C
solubility 490mg/l
form Crystals or Crystalline Needle
COA:
Product name | L-menthol | ||
CAS No. | 2216-51-5 | Outer Packing |
25kg/fiber can |
Production date | 20171018 | Shelf life | 2 years |
Standard adopted |
GB1886.199-2016 |
||
Items of analysis | Specification | Results | |
Appearance |
Colorless transparent prismatic or acicular crystal. |
Conforms |
|
fragrance |
Have a pleasant mint scent. |
Conform |
|
MP |
41.0ºC-44.0ºC |
42.0ºC-43.0ºC |
|
Subility(25ºC) |
The 1g sample was fully dissolved in 5ml190% (volume fraction) ethanol. |
Conform |
|
specific rotation(25ºC) |
-49°~-50° |
-49.9° |
|
Residue after evaporation |
≤0.05% |
0.02% |
|
Menthol content |
≥99.0% |
99.8% |
|
Conclusion | Qualified |
Usage:
L-Menthol is widely used in clinical and pharmaceutical practice for oral and topical formulations. Topical applications of L-Menthol includes the treatment of local pain, pruritus and allergic dermatitis. Oral formulations include the treatment of diggestive disorders, such as for example irritable bowel disease, and the use in the oral cavity due to its antiseptic and anesthetic properties. A further established application of L-Menthol is in form of inhalations for the symptomatic relief of sinusitis, rhinitis, bronchitis and similar condistions.
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