99% Tenofovir Disop...

99% Tenofovir Disoproxil Fumarate CAS 202138-50-9 For Treat AIDS Pharma Raw Materials

99% Tenofovir Disoproxil Fumarate CAS 202138-50-9 For Treat AIDS Pharma Raw Materials

Min.Order / FOB Price:Get Latest Price

100 Gram

Negotiable

  • Min.Order :100 Gram
  • Purity: 99%
  • Payment Terms : T/T,

Keywords

202138-50-9 Tenofovir Disoproxil Fumarate C23H34N5O14P

Quick Details

  • Appearance:White crystalline granules or powder.
  • Application:Used as a pharmaceutical intermediates.
  • PackAge:100g/ bag, 2 kg/ bag, 25kg/ carton or as required
  • ProductionCapacity:20000|Kilogram|Day
  • Storage:Store in sealed containers at cool & dry place. Protect from light, moisture and pest infestation.
  • Transportation:By DHL, TNT, FedEx, HKEMS, UPS, Etc

Superiority:

1. Guaranteed purity;

2. Large quantity in stock;

3. Largest manufacturer;

4. Best service after shipment with email;

5. High quality & competitive price;

 

Details:

Tenofovir Disoproxil Fumarate CAS 202138-50-9 For Treat AIDS Pharma Raw Materials

1. Description


Tenofovir disoproxil is an antiretroviral medication used to prevent and treat HIV/AIDS and to treat chronic hepatitis B. The active substance is tenofovir, while tenofovir disoproxil is a prodrug that is used because of its better absorption in the gut.

The drug is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. It is marketed by Gilead Sciences under the trade name Viread(as the fumarate, TDF). As of 2015 the cost for a typical month of medication in the United States is more than 200 USD.

2. Medical Applciation

HIV-1 infection: Tenofovir is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 2 years of age and older.[5] This indication is based on analyses of plasma HIV-1 RNA levels and CD4 cell counts in controlled studies of tenofovir in treatment-naive and treatment-experienced adults.

Tenofovir is indicated for the treatment of chronic hepatitis B in adults and pediatric patients 12 years of age and older.

 

3. Tenofovir Disoproxil Fumarate(TDF)

 

Food Interactions: None

Very well tolerated, side effects are minimal.

Toxicity:

Renal insufficiency(rare)

Must dose adjust with renal failure.

Also has activity against Hepatitis B.

Dosed 300mg QD.

Active against Lamivudine resistant HBV strains.

HBV resistance 1% at one year.

If TDF is stopped, may have HBV hepatitis flare.

 

Specification Sheet (COA)

 

 

 

Product name

Tenofovir Disoproxil Fumarate

CAS no.

202138-50-9

Items

Specifications

Results

Appearance

A White to off white crystalline powder

White crystalline powder

Solubility

Freely soluble in DMF and in methanol,sparingly soluble in water

Conform

Identification

A). By IR: Positive

Conform

B). By HPLC: Positive

Conform

Residue on ignition

0.2% max

complies

Water(By K.F)

1.0% max

0.4%

Heavy metals

20ppm max

Conform

Related Substance
(by HPLC)

a (Tenofovir): 0.15% max

Not detected

b (Adenine): 0.15% max

Not detected

c (Tenofovir isoproxil monoester): 1.0% max

0.29%

d (Tenofovir Disoproxil ethyl ester):0.15 max

Not detected

e (Tenofovir isopropyl isoproxil ): 0.3% max

Not detected

f (Tenofovir Disoproxil carbamate):0.15% max

Not detected

g (Tenofovir Disoproxil Dimer):0.15%

Not detected

Any Individual unspecified impuriy:0.1%

0.09%

Total impurity: 2.0% max

0.40%

Enantiomeric Purity

1.0% max

Not detected

Tenofovir Disoproxil Related compound B

5PPM max

Not detected

Fumaric Acid

17.5~19.0%

18.03%

Residual solvents

Ethanol: 5000ug/g max

1159ug/g

Isopropyl alcohol: 5000ug/g max

1077ug/g

Methylene chloride: 600ug/g max

Not detected

NMP: 530ug/g max

Not detected

Assay (on anhydrous basis)

98.0% to 102.0%

99.25%

Conclusion

Comply with USP34
 
Packaging & Shipping

 

 

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Advantages:

 

 

Hubei XinRunde Chemical Co., Ltd is a renowned pharmaceutical manufacturer. We can offer high quality products at competitive price in quick delivery with 100% custom pass guaranteed. Never stop striving to offer our best service is our philosophy. We have Flexible and Untraceable payment terms. As a leading manufacture, our products have been exported to Germany, Norway, Poland, Finland, Spain, UK, France, Russia, USA, Brazil, Mexico, Australia, Japan, Korea, Thailand, Indonesia, Uruguay and many other countries.


1. Quality.Every batch of steroid powders have tobetested by our QC(quality control) before they are allowed to sell.


2 . Delivery We have stock, so we can delivery quickly at the very day when receive the payment. Within 24 hours after receiving the payment Lead time 4 or 7 days.


3 . Discreet package Safelyand Professionally Disguised Package Guaranteed. For your safety and to insure delivery all products will be packed in a discreet way to prevent any suspicions, no steroids related name will appear on the parcels. high successful delivery rate

4 . Warm after-sale service Any of your question would be solved for the first as soon as possible.

 

 

Tenofovir Disoproxil Fumarate CAS 202138-50-9 For Treat AIDS Pharma Raw Materials

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