competitive price Poly(1-vinylpyrrolidone-co-vinyl acetate) 25086-89-9

Min.Order / FOB Price:Get Latest Price

1 Kilogram	Negotiable

1 Kilogram

Negotiable

Min.Order :1 Kilogram
Purity: 97%-99%
Payment Terms : T/T,Other

Keywords

25086-89-9 Poly(1-vinylpyrrolidone-co-vinyl acetate) C30H45N3O9X2

Quick Details

Appearance:Powder
Application:Poly(1-vinylpyrrolidone-co-vinyl acetate)
PackAge:as customer's request
ProductionCapacity:1|Kilogram|Day
Storage:Copovidone is stable and should be stored in a well-closed container in a cool, dry place.
Transportation:By sea/car

Superiority:

Henan CoreyChem Co., Ltd, based on the original Zhengzhou Cote Chemical Research Institute, be brave in absorbing highly educated talents & overseas returnees; actively responded to Zhengzhou City High-tech Zone Government’s Special Care Policy, reorganized and founded in National University of Science and Technology Park, which is a high-tech, stock enterprise of high-end chemical Custom synthesis;The park was created by the People's Government of Henan Province, and proved by Ministry of Education and the National Science & Technology, taking the construction mode of "many college a park, and common development", mainly depends on Zhengzhou University and Henan University’s scientific research and talent advantage to set up Universities, scientific research institute and enterprise scientific research achievements transformation platform, to make high-tech enterprises incubate, is the new high-tech talent gathering base, high and new technology industry enterprise radiation base, colleges and universities technological innovation base.

Henan Coreychem Co., Ltd, facing global High-tech pharmaceutical raw materials, high complex new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade. Corey have well-equipped machine, strong technical force and considerate marketing team service. We also have rich experience advantage in basic research, small scale process development, scale-up, industrial technology development & production and cost control.

Our R&D center building area is 811 square meters, with 3 contributing proffesor of technical advisor, 4 Dr., 10 masters, and 28 research staff. Our level of chemical synthesis is known to the industry. So we have accumulated rich experience in synthetic methods design and exploring the synthesis of new technology. Not only we are good in heterocyclic chemistry, chiral chemistry (asymmetric synthesis and enzyme reactions), metal organic synthesis, high throughput chemistry, also specializes in bioorganic chemistry, including nucleosides, nucleotides, sugar chemistry, peptide chemistry. R & D center has many sets of 10 liters, 20 liters, 50 liters, 100L multifunction high and low pressure reaction still, rotary evaporator, anhydrous anaerobic reaction devices, hydrogenation equipment, cryogenic process (-120 degrees) equipment, to complete mg level custom synthesis and kg level process development experiments. The Existing 600M NMR, LCMS, Fourier Infrared Spectrometer, liquid chromatography, differentialscanning calorimetry, and other advanced detection equipment areto ensure quality and efficient completion of R&D projects. So far our completed custom synthesis products is more than 5300 species, where dozens of them are non-CAS declaration products, almost including all types of organic reactions.

At present, in addition to our headquarters in Zhengzhou, we also have another product base in Jun County, Henan Province. This base is the attracting investment of science and technology project of Jun County govenment’s, which covers 6529 square meters. In addition to bear our own company’s 1000L-5000L pilot task, also bear the function of Henan pilot incubation service platform, In order to improve Henan and surroundings’ synthetic reaction pilot service ability and the key technology development capabilities. Base with three GMP standards workshop, a testing center, one test center,one experiment center and associatd supporting facilities, can carry out oxidation, hydrogenation (70 kg pressure), halogenated, acieration, etherification, condensation, cyclization, formatting, ammoniated, diazotization andpilot service such as azide reactions etc. In the future we will work hard to make it become the most complete production system in central China and even the whole country, the highest technical level, the strongest talent team, the most popular service scope of pilot incubation service platform.

Henan Coreychem co., LTD. is committed to provide cost effective chemical service to the global fine chemical industry product development agencies; we adhering to the consistent good commercial reputation, to create a highly efficient, high quality of chemical research, development, production, sales and service of integrated platform, let our customers faster, better get ideal and thoughtful service.

Coreychem

Henan CoreyChem Co., Ltd, facing global High-tech pharmaceutical raw materials, high value-added new type intermediates, fine chemicals custom synthesis, scale-up production and Rare chemicals trade.

Innovative

Henan Coreychem is committed to continuously explore new compound synthesis technology in recent years,we were on enzyme catalysis, catalytic metal complexes in the total synthesis was tested and achieved good results: S.lycopersicum (+) - Aszonalenin (+) - Citrinadin B Total Synthesis of ( − )-Brevicompanine B by Ir-Catalyzed Total Synthesis of (+)-Citrinadin B

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Poly(1-vinylpyrrolidone-co-vinyl acetate) Basic information

Product Name:	Poly(1-vinylpyrrolidone-co-vinyl acetate)
Synonyms:	copolyresinvinylketopyrrolidine/vinylacetate;copolyvidon;e335;e535;gaf-s630;ganexe535;gantronpvp;gantrons630
CAS:	25086-89-9
MF:	C30H45N3O9X2
MW:	591.69
EINECS:
Product Categories:	Hydrophobic Polymers;Materials Science;Hair Care;Polymer Science;Vinylpyridine and Vinypyrrolidone Polymers;API;Polymers;Hydrophobic Polymers;Poly(vinylpyrrolidone);Vinylpyridine and Vinypyrrolidone Polymers
Mol File:	25086-89-9.mol

Poly(1-vinylpyrrolidone-co-vinyl acetate) Chemical Properties

density	1.27 g/mL at 25 °C(lit.)
refractive index	1.4300 to 1.4380
Fp	72 °F
solubility	Greater than 10% solubility in 1,4-butanediol, glycerol, butanol, chloroform, dichloromethane, ethanol (95%), glycerol, methanol, polyethylene glycol 400, propan-2-ol, propanol, propylene glycol, and water. Less than 1% solubility in cyclohexane, diethyl ether, liquid paraffin, and pentane.
form	powder
Stability:	Stable. Combustible, especially in powdered form. Incompatible with strong oxidising agents, strong reducing agents.
EPA Substance Registry System	Acetic acid ethenyl ester, polymer with 1-ethenyl-2-pyrrolidinone(25086-89-9)

Safety Information

Hazard Codes	Xi,F
Risk Statements	10-36/37/38-67-36-11-22
Safety Statements	22-24/25-36/37/39-26-16
RIDADR	UN 1987 3/PG 2
WGK Germany	1
RTECS	AH3539000
HazardClass	3
PackingGroup	II
HS Code	29349990

MSDS Information

Provider	Language
SigmaAldrich	English

Poly(1-vinylpyrrolidone-co-vinyl acetate) Usage And Synthesis

Chemical Properties	white powder
Chemical Properties	Copovidone is a white to yellowish-white amorphous powder. It is typically spray-dried with a relatively fine particle size. It has a slight odor and a faint taste.
Uses	Poly(1-vinylpyrrolidone-co-vinyl acetate)
Production Methods	Copovidone is manufactured by free-radical polymerization of vinylpyrrolidone and vinyl acetate in a ratio of 6 : 4. The synthesis is conducted in an organic solvent owing to the insolubility of vinyl acetate in water.
Pharmaceutical Applications	Copovidone is used as a tablet binder, a film-former, and as part of the matrix material used in controlled-release formulations. In tableting, copovidone can be used as a binder for direct compression and as a binder in wet granulation. Copovidone is often added to coating solutions as a film-forming agent. It provides good adhesion, elasticity, and hardness, and can be used as a moisture barrier.
Safety	Copovidone is used widely in pharmaceutical formulations and is generally regarded as nontoxic. However, it is moderately toxic by ingestion, producing gastric disturbances. It has no irritating or sensitizing effects on the skin. A study was conducted to look at the carcinogenicity and chronic toxicity of copovidone (Kollidon VA 64) in Wistar rats and Beagle dogs. The results of these studies demonstrated the absence of any significant toxicological findings of high dietary levels of copodivone in rats and dogs, resulting in noobserved- adverse-effect levels of 2800 mg/kg body-weight/day in rats and 2500 mg/kg body-weight/day in dogs, the highest doses tested. LD₅₀ (rat, oral): >0.63 g/kg
storage	Copovidone is stable and should be stored in a well-closed container in a cool, dry place.
Incompatibilities	Copovidone is compatible with most organic and inorganic pharmaceutical ingredients. When exposed to high water levels, copovidone may form molecular adducts with some materials; see Crospovidone and Povidone.
Regulatory Status	Copovidone is included in the FDA Inactive Ingredients Database (oral tablets, oral film-coated tablets, sustained action).