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Disodium 5′-Inosinate Disodium 5′-Inosinate Powder C10H11N4Na2O8P
CAS Number: | 4691-65-0 |
Purity: | ≥99% |
Molecular Weight: | 392.17 |
Molecular Formula: | C10H11N4Na2O8P |
EINECS | 225-146-4 |
Appearance: | White to off-white powder or crystalline powder |
Physical State | Solid |
Solubility: | slightly soluble in water, insoluble in ethanol |
Storage: | Preserve in tight containers,in a cool and dry place. |
5'-Nucleotides are produced through the hydrolytic reaction from Ribonucleic acid(RNA) as raw material by enzymatic catalysis to form four kinds of nucleotides 5- 'AMP (adenosine-5'-monophosphate), 5'-GMP•2Na(guanosine-5'-monophosphate, disodium salt), 5'-CMP(cytidine-5'-monophosphate)-, 5'-UMP•2Na (uridine- 5'-monophosphate,Disodium salt) .By the chromatographic isolation, four kinds of separated 5'-nucleotide products with high purity can be obtained. These products can be widely applied in medicine, reagent, fine chemical industry, and additive of food fields etc.
The Metabolism of Nucleotides
Before we look at nucleic acid structure, we need to study the synthesis of the purine and pyrimidine ribonucleotides and the subsequent synthesis of the deoxyribonucleotides, followed by their catabolic and recycling pathways. The synthetic pathways are particularly detailed, and I suggest that you review my introduction to the study of biochemical pathways so that you can break the information down into manageable pieces. Along the way, we will correlate the information, where appropriate, to disease states. In such instances, I will use the header "Clinical Correlate".
Purine Ribonucleotide Synthesis
Surprisingly, the purine ribonucleotides are formed as such de novo, and the bases themselves are derived from them. The first purine ribonucleotide to be synthesized in an organism is inosine monophosphate.
5'-Nucleotides are produced through the hydrolytic reaction from Ribonucleic acid(RNA) as raw material by enzymatic catalysis to form four kinds of nucleotides 5- 'AMP (adenosine-5'-monophosphate), 5'-GMP•2Na(guanosine-5'-monophosphate, disodium salt), 5'-CMP(cytidine-5'-monophosphate)-, 5'-UMP•2Na (uridine- 5'-monophosphate,Disodium salt) .By the chromatographic isolation, four kinds of separated 5'-nucleotide products with high purity can be obtained. These products can be widely applied in medicine, reagent, fine chemical industry, and additive of food fields etc.
Application
Widely used in medicine, health products, food, beverage, cosmetics, biological and chemical reagents and other industries.
Inosinic acid can be converted into various salts including disodium inosinate (E631), dipotassium inosinate (E632), and dicalcium inosinate (E633). These three compounds are used as flavor enhancers with a comparatively high effectiveness. They are mostly used in soups, sauces, and seasonings for the intensification and balance of meat taste.
Item |
Specification |
Results |
Physical Property |
||
Appearance |
White Powder |
Conforms |
Odor |
Characteristic |
Conforms |
General Analysis |
||
Identification Assay (Test by HPLC) Loss on Drying |
Identical to sample 99% - 101% ≤1.0% |
Conforms 99.88% 0.39% |
Specific Rotation |
+20.0 ~+22.0° |
Conforms |
Ash |
≤3.0% |
0.68% |
Contaminants |
||
Lead (Pb) |
≤3.0mg/kg |
2.2 |
Arsenic (As) |
≤2.0mg/kg |
1.6 |
Cadmium (Cd) |
≤1.0mg/kg |
0.5 |
Mercury (Hg) |
≤0.1mg/kg |
0.06 |
Microbiological |
||
Total Plate Count |
≤1000cfu/g |
Conforms |
Yeast&Mold |
≤100cfu/g |
Conforms |
E.Coli. |
Negative |
Conforms |
Salmonella |
Negative |
Conforms |
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