Bicalutamide USP Grade 98%min
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| 1 Gram |
FOB Price:USD 450.0000 -500.0000 |
- Min.Order :1 Gram
- Purity: 99%
- Payment Terms : L/C,T/T,
Keywords
Bicalutamide 90357-06-5 Bicalutamide USP Grade
Quick Details
- Appearance:white or almost white crystal powder
- Application:Prostate drug
- PackAge:25kgs cardboard drum
- ProductionCapacity:1|Metric Ton|Month
- Storage:Cool, dry, shading, and sealed storage.
- Transportation:Express, air or sea
Superiority:
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Details:
Bicalutimide
CAS RN: 90357-06-5
Chemical name: N-[4-Cyano-3-（trifluoromethyl）phenyl]-3-[（4-fluorophenyl）sulfonyl]-2-hydroxyl-2- methylpropanemide
Synonyms: Bicalutamide (Subject to patent free); 4-cyano-3-trifluoromethyl-N-(3-p-fluorophenylsulfonyl-2-hydroxy-2-methylpropionyl)aniline; N-[4-cyano-3-(trifluoromethyl)phenyl]-3-(4-fluorophenyl)sulfonyl-2-hydroxy-2-methyl-propanamid; [(4- fluorophenyl) sulfonyl]-2-hydroxy- 2-methyl propanamide ; N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide; (2S)-N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluorophenyl)sulfonyl]-2-hydroxy-2-methylpropanamide
Molecular formula:C18H14F4N2O4S
molecular weight: 430.38
Characters: It’s a white or almost white crystal powder, odorless, tasteless, freely soluble in DMF; Soluble in butylene oxide; sparingly soluble in acetic ether and methanol; insoluble in water.
Quality Standard: EP9.0/USP39
Specification:
| Item | Standard |
| Appearance | White to off-white powder |
| Solubility | Freely soluble in tetrahydrofuran and acetone; soluble in acetonitrile; sparingly soluble in methanol; slightly soluble in alcohol. |
| Identification | |
| A: infrared spectrum | Infrared absorption spectrohotometry confirm |
| B: hplc | The sample spectrum corresponds to standard |
| Specific optical rotation | +25.0° ～+27.5° |
| Residue on Ignition | NMT 0.1% |
| Heavy metals | NMT 10ppm |
| Water | NMT 0.2% |
| Organic impurities | NMT 0.1% |
| Bicalutamide aminobenzonitrile | NMT 0.1% |
| Bicalutamide relate compound A isomer A | NMT 0.1% |
| Bicalutamide relate compound A isomer B | NMT 0.1% |
| Desfluoro bicalutamide | NMT 0.2% |
| 2-Fluoro bicalutamide | NMT 0.2% |
| Deoxybicalutamide | NMT 0.2% |
| Bicalutamide sulfide | NMT 0.1% |
| Any unspecified impurity | NMT 0.1% |
| Total impurities | NMT 0.5% |
| Residual Solvent | DMAC≤1090ppm |
| Ethanol≤1000ppm | |
| Dichloromethane≤300ppm | |
| Ethyl acetate≤1000ppm | |
| MIBK≤1000ppm | |
| Petroleum ether≤1000ppm | |
| Benzene≤2ppm | |
| Assay | 98.0%-102.0% |
Usage:
Prostate drug, It is developed by AstraZenca Internatioal,and it is the first antiandrogen non-corticosteroids drug for long-acting oral medication and firstly go on the market in 1995 in UK. An antiandrogen non-corticosteroids can be used treating prostate cancer in advanced stage as assistant drug, may also for treating prostate cancer in the early stage to play an important role.
Storage:
It should be kept in room temperature, and away from light; stored in sealed containers.
Packing: paper bucket, 25kg/package.
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