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Cytosine arabinoside Cytosine CAS 147-94-4
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product Name | cytosine-1-beta-D-arabinofuranoside |
---|---|
Synonyms | Cytosine 1-beta-D-arabinofuranoside; 1-b-D-Arabinofuranosylcytosine; cytarabine; cytosine arabinoside; 4-amino-1-beta-d-arabinofuranosyl-2(1h)-pyrimidinone; arabinocytidine; 4-amino-1-pentofuranosylpyrimidin-2(1H)-one; 4-amino-1-(beta-D-arabinofuranosyl)pyrimidin-2(1H)-one; 4-amino-1-(D-arabinofuranosyl)pyrimidin-2(1H)-one; N-(2-oxo-2,3-dihydropyrimidin-4-yl)-D-arabinofuranosylamine; 4-amino-1-[(2R,4R,5R)-3,4-dihydroxy-5-(hydroxymethyl)tetrahydrofuran-2-yl]pyrimidin-2-one |
Molecular Formula | C9H13N3O5 |
Molecular Weight | 243.2166 |
CAS Registry Number | 147-94-4 |
EINECS | 205-705-9 |
Molecular Structure |
|
Density | 1.89g/cm3 |
Boiling point | 545.7°C at 760 mmHg |
Refractive index | 1.756 |
Flash point | 283.8°C |
Vapour Pressur | 3.5E-14mmHg at 25°C |
Hazard Symbols | Xn:Harmful; |
Risk Codes |
R43:; R63:; |
Safety Description | S36/37:; |
Specification: USP
Appearance |
White to off-white crystalline powder |
Conforms |
Solubility |
Freely Soluble in water, very slightly soluble in alcohol and in methylene chloride. |
Conforms |
Identification |
A. IR |
Conforms |
B. HPLC |
Conforms |
|
Loss on drying |
≤1.0% |
0.02% |
Specific rotation |
Between +154°and +160° |
+158.5° |
Heavy metal |
≤10ppm |
Conforms |
Residue on ignition |
Not more than0.5% |
0.18% |
Chromatographic purity |
Total : Not more than 0.30% |
0.13% |
Individual : Not more than 0.10% |
0.03% |
|
Uracil arabinoside:Not more than 0.30% |
0.02% |
|
Residual solvents |
Ethanol≤5000ppm |
105ppm |
Methanol≤3000ppm |
180ppm |
|
Acetonitrile≤410ppm |
Not found |
|
Assay |
Between 98.0% and 102.0 % |
100.1% |
Control Hygienic |
Total aerobic microbial count: does not exceed 100cfu/g |
Conforms |
Molds and yeasts count: does not exceed 10cfu/g |
Conforms |
|
Escherichia coli,Staphylococcus aureus,Pseudomonas aeruginosa: Absence/g |
Not found |
|
Conclusion : |
The product complies with USP 32 standard. |
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