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10 Gram |
Negotiable |
HBT1 YDL223C CAS 489408-02-8
HBT1 CAS 489408-02-8 Basic information | |
CAS | 489408-02-8 |
Assay | 98.0%min(HPLC) |
Chemical name or material | 2-(((5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl)acetyl)amino)-4,5,6,7-tetrahydro-1-benzothiophene-3-carboxamide; HBT1; HBT-1; HBT 1 |
Molecular Formula | C16H17F3N4O2S |
Molecular Weight (g/mol) | 386.39 |
HBT1 CAS 489408-02-8 Chemical Properties | |
Exact Mass | 386.1024 |
Solubility | DMSO: 2 mg/mL, clear |
InChI Key | PHLXSNIEQIKENK-UHFFFAOYSA-N |
Smiles | O=C(C1=C(NC(CN2N=C(C(F)(F)F)C=C2C)=O)SC3=C1CCCC3)N |
Moisture | 0.5%Max |
Physical state | Powder |
Application | Intermediate in organic syntheses |
Production Scale | Up to kgs |
HBT1 CAS 489408-02-8 Description:
HBT1 is a novel potent AMPA-R [alpha-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid (AMPA) receptor] potentiator with lower agonistic effect compared with LY451395 and OXP1, it induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate dependent manner.
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