Entrectinib RXDX-101 RXDX101
Entrectinib, also known as RXDX-101 and NMS-E628, is an oral small molecule inhibitor of TrkA, TrkB and TrkC, as well as ROS1 and ALK, with high potency and selectivity. RXDX-101 has demonstrated potent pharmacological activity in preclinical studies and has the potential to be first-in-class against the Trk family of kinases. PXDX-101 has been well tolerated in patients with advanced solid tumors.
Technical Data Sheet
Item | Entrectinib |
CAS | 1108743-60-7 |
MF | C31H34F2N6O2 |
Boiling point | 717.5±60.0 °C(Predicted) |
density | 1.340±0.06 g/cm3(Predicted) |
pka | 12.01±0.43(Predicted) |
Packing and shipping
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