Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2

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0 Metric Ton	Negotiable

0 Metric Ton

Negotiable

Min.Order :0 Metric Ton
Purity: 95%

Keywords

Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH2 140430-53-1 Mca-PLGL-Dpa-AR-NH2

Quick Details

Appearance:
Application:Cancer Research
PackAge:
ProductionCapacity:|Metric Ton|Day
Storage:-20 ± 5 °C
Transportation:

Superiority:

Nanjing TGpeptide Biotechnology Co.,Ltd.("TGpeptide" hereafter), who is founded in 2019, located at Jiangbei New Material Industrial Park, is a professional enterprise enageged in researching, developing, manufacturing and sales of peptide, antibody and protein products and their technologies.
Range of Services：
1, Linear peptides: Quantity from mg to kg, up to 180 residues.
2, The range of purity: Crude、Desalted、＞70%、＞80%、＞90%、＞95%、＞98%、＞99%.
3, Peptide modifications: C-terminal modifications, N-terminal modifications, Fluorescence and Dye Labeling Peptides, Cyclic Peptides Synthesis, Phosphopeptides etc.
4, Peptides with different structures: Linear peptides, MAPs, Cyclic peptides etc.
5, Antigen peptides: KLH, BSA, 0VA coupling.
6, Different packages: we can make aliquots according to the demand of customers, and it's free.

Details:

173P21

Mca-Pro-Leu-Gly-Leu-Dap(Dnp)-Ala-Arg-NH? trifluoroacetate salt

Mca-PLGL-Dpa-AR-NH?

7-Methoxycoumarin-4-Acetyl-Pro-Leu-Gly-Leu-Dnp-(2,3-Diaminopropionyl)-Ala-Arg, amide

C??H??N??O??

1093.16

140430-53-1

Synthetic

-20 ± 5 °C

Cancer Research

Mca-PLGL-Dpa-AR-amide is a very sensitive FRET substrate for continuous assays and in situ determination of the matrix metalloproteinase activity. Cleavage at the Gly-Leu bond separates the highly fluorescent Mca group from the efficient 2,4-dinitrophenyl quencher, resulting in an increase in fluorescence intensity. The kcat/Km values for the punctuated metalloproteinase (MMP-7) and for gelatinase (MMP-2), e.g., are 1.7·10? and 6.3·10? M?¹s?¹, respectively.

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