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Linaelotide Whole Sale Price Linaelotide Manufacturer China 851199-59-2
Yinherb Linaclotide/Linaelotide Acetate Peptide Bulk powder
Name:Linaclotide Acetate
Cas No:851199-59-2
Formula: C61H83N15O23S6
Molecular: 1586.78
Sequence: Cys cys glu tyr cys cys asn pro ala cys thr gly cys tyr (disulfide bridge: 1-6; 2-10; 5-13)
Purity:98%
Appearance: white powder
Source: synthetic
Also known as: MM-416775, Linaclotide acetate (USAN), Linaclotide acetate [USAN], 851199-60-5, MD-1100 acetate, UNII-NSF067KU1M
Minimum Order Quantity: 1 g
Brand Name: Yinherb
Test Method: HPLC
Storage: Lyophilized peptides although stable at room temperature for 3 months, should be stored desiccated below -18° C. Upon reconstitution of the peptide it should be stored at 4° C between 2-21 days and for future use below-18° C.
What is Linaclotide/Linaelotide Acetate Peptide
Linaclotide is an administered, peptide agonist of guanylate cyclase 2C for the treatment of irritable bowel syndrome. Chemically, it is a heterodetic cyclic peptide and consists of fourteen amino acids.
Linaclotide/Linaelotide Acetate Peptide Benefits
Linaclotide is used to treat certain types of bowel problems (irritable bowel syndrome with constipation, chronic idiopathic constipation). It works by increasing fluid in your intestines and helping speed up movement of food through the gut. Linaclotide may improve stool texture and lessen symptoms such as bloating, abdominal pain/discomfort, straining, and feelings of incomplete bowel movements. FDA approved on August 30, 2012.
Linaclotide reduces activation of colonic sensory neurons, reducing pain; and activates colonic motor neurons, which increases smooth muscle contraction and thus promotes bowel movements. It was approved by the FDA in August 2012 for the treatment of chronic idiopathic constipation and constipation predominant irritable bowel syndrome (IBS-C) in adults.
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