CasNo.54024-22-5,Competitive price of 54024-22-5 prompt delivery desogestrel powder,(54024-22-5) Suppliers

1 Gram	FOB Price: USD 99.0000

Min.Order :1 Gram
Purity: 99%
Payment Terms : L/C,D/A,D/P,T/T

Keywords

prompt delivery desogestrel Desogestrel powder Competitive price of 54024-22-5

Quick Details

Appearance:powder
Application:Oral powerful progestational hormone
PackAge:tin
ProductionCapacity:10|Metric Ton|Year
Storage:keep out of the sun
Transportation:by sea, by air

Superiority:

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Details:

Product Categories	Pharmaceuticals /API / hormone drug
Synonyms	13-Ethyl-11-methylene-18,19-dinor-17alpha-pregn-4-en-20-yn-17-ol
CAS No.	54024-22-5
EC No.	258-929-4
Molecular Weight	310.473
Molecular Formula	C₂₂H₃₀O
Standard	EP; USP
Package	1kg/tin
Product Introduction	White or almost white crystalline powder
Use	Oral powerful progestational hormone
Product Name	Destogestrel

Desogestrel , (17α)-13-ethyl-11-methylene-18,19-dinorpregn-4-en-20-yn-17-ol, is a 19-nortestosterone analog with good progestin activity. Likethe other progestins, it is orally active and used in combinationwith an estrogen in oral contraceptives. Desogestrel is aprodrug that must be oxidized to the 3-one in vivo to haveprogestational action. CYPs 2C9 and 2C19 have been implicatedin the initial hydroxylation of desogestrel at C3.

Clinical Use Desogestrel also is a prodrug and is rapidly metabolized in the intestinal mucosa and on first pass through the liver to its active metabolite, etonogestrel (3-ketodesogestrel). Following oral administration, the relative bioavailability for desogestrel is approximately 84%. Desogestrel also exhibits high selectivity for the progesterone receptor and low and rogenic activity, and it does not diminish the beneficial effects of estrogen on the lipid profile.