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Diosmin +hesperidin powder 520-26-3 Hesperidin powder GMP hesperidin
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Sell Hesperidin Powder 520-26-3 GMP Factory
Description
Hesperidin exists mainly in the peel of lemon, orange, and Seville orange flower, which belong to facilitating medicine. These Chinese medicines are warm and fragrant with the function of eliminating depression and knots. They cure abdominal distension, belching swallow acid pain, nausea and vomiting, diarrhea or constipation caused by the spleen, and stomach qi zhi; and they also cure depression, hernia, breast pain, and menoxenia caused by liver qi; moreover, they cure chest pain, cough, and asthma, which are caused by lung qi.
Modern research has shown that li qi medicines have an extensive effect, such as regulatory effect on the digestive system, and they control the bronchial smooth muscle, the uterus smooth muscle, and the cardiovascular system. The base of the effect of li qi medicines in inverse, anti-nausea, antidiarrheal, and analgesia pharmacological effects is its effect in inhibiting gastric bowel movement; its exciting gastrointestinal movement is the foundation to eliminate swelling; its effect in relaxation of the bronchial smooth muscle is the foundation of pharmacological effects in antinausea. The intravenous injection to treat shock effect is the new development of li qi medicine.
Hesperidin is a flavanone rutinoside first isolated from citrus peels. It is metabolized by intestinal bacteria to an aglycone form, hesperetin (Item No. 10006084), which is thought to be more bioavailable due to reduced polarity that allows for increased cell permeability. At 100 μM, hesperidin has been shown to increase the cytotoxicity of doxorubicin (Item No. 15007) on MCF-7 and HeLa cancer cells in vitro by inhibiting cell cycle progression and upregulating apoptosis. It also is reported to produce estrogenic effects, decreasing serum and hepatic lipid concentrations and reducing osteoporosis in ovariectomized rats. Hesperidin produces free radical scavenging activity in various in vitro antioxidant assays.
Properties
Hesperidin Chemical Properties |
Melting point | 250-255 °C (dec.)(lit.) |
alpha | -76 º (c=2,pyridine) |
Boiling point | 576.16°C (rough estimate) |
density | 1.3290 (rough estimate) |
refractive index | 1.5940 (estimate) |
storage temp. | Sealed in dry,2-8°C |
pka | 7.15±0.40(Predicted) |
form | Powder |
color | light brown |
Water Solubility | Insoluble in water. Soluble in organic solvents such as DMSO. |
Sensitive | Hygroscopic |
Merck | 14,4671 |
BRN | 75140 |
Stability: | Stable. Incompatible with strong oxidizing agents. |
InChIKey | QUQPHWDTPGMPEX-QJBIFVCTSA-N |
CAS DataBase Reference | 520-26-3(CAS DataBase Reference) |
EPA Substance Registry System | Hesperidin (520-26-3) |
Application
1. Vitamin P is considered a vascular protector and an anti-inflammatory agent, vitamin P is said to promote capillary health and increase resistance to collagen destruction. Vitamin P is a bioflavonoid that can work in conjunction with vitamin C, helping prevent oxidation of the latter. Vitamin P is found in such food sources as apricots, broccoli, citrus fruit pulp, grapes, prunes, and spinach.
2. Hesperidin is a flavoring agent that is a bioflavonoid found in citrus pulp. it has minor use as a flavorant.
3. A flavanone found in citrus fruits, also regarded as Vitamin P.
4. Antiinflammatory, capillary protectant, hypolipidemic
5. Anticancer
Factoy Superiority
We supply high quality TRANEXAMIC ACID API as well as its intermediates with over more than 10 years experience in production.
We have multiple grades on this API. We can supply BP, EP, JP, injection etc. With annual selling of more than 10 tons. It can be used in many aspects, such as in facial cream and in tabs etc. Either aspect we can provide accordingly materials.
We have full documentation support on this product, and it is on regular basis production. Feel free to contact us if you would develop this product or in search of an alternative source of provision.
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