ORM-15341

ORM-15341

ORM-15341

Min.Order / FOB Price:Get Latest Price

10 Milligram

Negotiable

  • Min.Order :10 Milligram
  • Purity: 98% 99%

Keywords

ORM-15341 1297537-33-7 C19H17ClN6O2

Quick Details

  • Appearance:
  • Application:antagonist for human AR (hAR)
  • PackAge: 5mg 10mg 25mg
  • ProductionCapacity:|Metric Ton|Day
  • Storage: -20℃
  • Transportation:by sea or by air

Superiority:

ORM-15341 is a potent and full antagonist for human AR (hAR) with IC50 values of 38 nM as shown by transactivation assays in AR-HEK293 cells stably expressing full-length hAR and an androgen-responsive luciferase reporter gene construct.IC50 value: 38 nMTarget: androgen receptorin vitro: In competitive AR binding assays, the inhibition constant (Ki) values of ORM-15341 was 8 nM. ORM-15341 functions as a full antagonist for all tested mutant ARs , with IC50 of 25, 51, 700, and 1160 nM for wtAR, AR(F876L), AR(T877A), and AR(W741L).

Details:

Yichang shangnuoder Biomedical Technology Co., Ltd. was registered and established in September 2018, located in the national biomedical incubator of Yichang City, Hubei Province (Chengdong u Valley). It is a comprehensive high-tech enterprise integrating R & D, production and sales of pharmaceutical raw materials and intermediates.
 
 
The company has a 400 square meter standard chemical synthesis laboratory, advanced production equipment, and a strong R & D team composed of several senior technical researchers with bachelor's degree and master's degree. It has established the "production, teaching and research" cooperation mode with some universities in Yichang, Wuhan and Shanghai. The company is mainly engaged in the R & D and production of new chemical drugs, high-end chemicals and pharmaceutical intermediates, and has applied for 12 patents in key technology fields.
 
Since its establishment, the company has been adhering to the business philosophy of "innovation driven, efficiency first, professional guidance, first-class service", continuously providing high-quality products and services to customers at home and abroad, providing services throughout Wuhan, Hangzhou, Shanghai, Shenzhen and other regions, accumulating rich business resources. After years of technical development, the company can provide customers with mature and stable high-level pharmaceutical raw materials, intermediate R & D, manufacturing and other professional services.

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