Buy Top Purity Piceatannol 10083-24-6 Powder With Best Price

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Buy Top Purity Piceatannol 10083-24-6 Powder With Best Price

Description

Piceatannol is a stilbene and a hydroxyl derivative of resveratrol, obtained from the seeds of Euphorbia lagascae. It was reported to possess antiproliferative, antioxidant, antiinflammatory effects, and chemopreventive properties. Piceatannol exhibited the ability to upregulate the expression of HO-1 and its mRNA transcription in human epithelial cells. It was also able to activate nuclear translocation of Nrf2 and its expression and enhance the pertinent transcriptional activities in the MCF10A cells. It induces apoptosis via activation of caspase-3. The catechol functionality of piceatannol may assist in binding to Keap1 and thus is essential for activation of Nrf2 and subsequently induction of HO-1.

Properties

Applications

1. It is an anti-inflammatory, immunomodulatory and antiproliferative agent. It inhibits p56lck and syk protein tyrosine kinases, and inhibits NF-κB activation and gene expression of TNF-κB. It is transformed by cytochrome P4501B1 Synthetic resveratrol.

2. A plant metabolite with anti-leukemia activity; inhibits non-receptor activating enzyme, spleen tyrosine kinase and lymphocyte-specific protein tyrosine kinase. (It can inhibit the growth and development of immature fat cells, thereby achieving the goal of weight loss. In addition, paclitaxel can also help prevent cancer, heart disease and neurological diseases)

3. Paclitaxel has a moisturizing effect for dry skin.