Isoprinosine,High p...

Isoprinosine,High purity
Isoprinosine,High purity

Isoprinosine,High purity

Min.Order / FOB Price:Get Latest Price

1 Gram

Negotiable

  • Min.Order :1 Gram
  • Purity: >99.0%
  • Payment Terms : T/T,Other

Keywords

36703-88-5 High purity Isoprinosine Inosine pranobex

Quick Details

  • Appearance:White or off-white crystalline powder
  • Application:Pharmaceutical Intermediate
  • PackAge:1kg/bag, 10kg/drum, 25kg/drum (on request)
  • ProductionCapacity:1|Metric Ton|Month
  • Storage:Cool, shading, dry and sealed/2years
  • Transportation:By courier,by air,by sea

Superiority:

ISOPRINOSINE(36703-88-5)                                                                                

Information

Isoprinosine is an antiviral drug that can increase peripheral blood lymphocytes, lymphocyte transformation rate and IFN level in children. The drug has been used for SSPE for nearly 20 years. Most studies have shown that the drug can improve or stabilize the symptoms of some children and increase the survival rate. It is often used in combination with IFN.

Quality

Advanced technology

Supper quality

Effective & safety package

Service

Professional and timely afte-sale service(replied within 12h)

COMPANY INFORMATION                                                                                 

Jinan Kangcheng Pharmaceutical Technology Co., Ltd.

Add:Jinan Area,China(Shandong) Pilot Free Trade Zone,China

The company focuses on the development and transfer of pharmaceutical technology. It is a modern enterprise integrating technology development, transfer and sales of APIs, pharmaceutical intermediates, and nutraceutical raw materials.

The company adheres to the principle of integrity and innovation, and provides customers with professional products and advanced technical services.

Details:

INOSINE PRANOBEX

Product information

English Name:Inosine pranobex

English Alias:Inosine pranobexIsoprinosine

Chinese Name:异丙肌苷

Chiners Alias:异丙基肌酐

CAS号:36703-88-5

Formula:C52H78N10O17

Molecular weight:1115.23

Appearance:White or off-white crystalline power

Purity:99.0%

Use&Pharmacology

Isoprinosine is an antiviral drug that can increase peripheral blood lymphocytes, lymphocyte transformation rate and IFN level in children. The drug has been used for SSPE for nearly 20 years. Most studies have shown that the drug can improve or stabilize the symptoms of some children and increase the survival rate. It is often used in combination with IFN.

This product is mainly used for herpes simplex virus infection and genital warts. It can also improve the immune function of patients with primary tumors such as lung cancer, breast cancer, and melanoma. Generally, the immune function can be maintained for 2 months after each administration. Isoprinosine also has certain effects on autoimmune diseases such as rheumatoid arthritis, including slowing down erythrocyte sedimentation rate, reducing fibrinogen, reducing the number of swollen joints, and reducing morning stiffness. It is also effective for multiple angular cheilitis and focal genitalitis.

Isoprinosine has antiviral effects and is effective for human herpes, flu and nasal infections. The curative effect is better for patients with herpes simplex virus infection. In addition to its direct antiviral effect, this product also has an immune-enhancing effect, mainly to enhance cellular immune function. Clinical studies have shown that it can increase the proliferation of lymphocytes caused by mitotic factors, increase the production of antibodies, and increase the production of cytokines, such as interleukin-2. This product has the characteristics of high curative effect and small side effects.

Isopinosine is a 1:3 compound composed of inosine and dimethylaminoisopropanol acetamidobenzoate. It is a chemically synthesized immunomodulator and is used in the pharmaceutical industry to treat influenza virus, herpes virus, Viral diseases such as immunodeficiency virus infection. The main pharmacological effects of isopinosine are as follows:

(1) Isoprinosine can promote the proliferation of lymphocytes induced by phytohemagglutinin (PHA), concanavalin A (ConA), tetanus toxoid, influenza virus, etc.

(2) Enhance delayed-type allergic reactions caused by dinitrochlorobenzene, and return to normal delayed-type allergic reactions inhibited by cyclophosphamide.

(3) Restore the proliferative response of mouse spleen lymphocytes to ConA, which is inhibited by cyclophosphamide.

(4) This product can also promote the production of interleukin 1 (IL-1), interleukin 2 (IL-2) and interferon, and enhance the activity of mononuclear macrophages and natural killer cells (NK). This product can also restore normal immune function due to aging, including decreased lymphocyte proliferation caused by aging, NK cytotoxicity, monocyte chemotaxis, and plaque forming cells. Normal or close to normal.

This product is rapidly absorbed and metabolized after oral or intravenous administration. The plasma concentration reached its peak 1 hour after oral administration, and then dropped to disappear after 2 hours. The main excretion product is uric acid, and other metabolites are excreted in the urine after oxidation or glucuronidation. The oral plasma half-life is 50 minutes, and the intravenous half-life is 3 minutes.

This product treats 200 homosexual or heterosexual male patients with lymphadenopathy and AIDS-related complex diseases. As a result, the NK cell function and delayed allergic reactions of some patients have been significantly improved. After culturing the monocytes of patients with AIDS and AIDS-related complexes together with isopinosine in vitro, it can be seen that the mitogen-induced lymphocyte proliferation response and the enhancement of NK cell activity can promote interferon and IL- The production of 2 increases the ratio of CD4 cells and the number of cells expressing IL-2 receptors

Adverse reactions

After oral administration, there are short-term gastrointestinal reactions such as nausea and vomiting. The inosine part of this product is finally metabolized into uric acid in the body, which can temporarily increase uric acid in serum and urine.

Package&Storage

Package:1kg/bag, 10kg/drum, 25kg/drum (on request)

Storage&Validity:Cool, shading, dry and sealed/2years

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