The role of 4-hydroxyethylpiperazine ethanesulfonic acid (HEPES) in cosmetics

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Everyone has the love of beauty. In recent years, women have paid more and more attention to skin care, so more and more whitening and anti-aging cosmetics have appeared. As consumers pay more attention to cosmetic ingredients and brands focus on ingredients, more and more cosmetic additives, such as hyaluronic acid, niacinamide, HEPES, etc., have come into the public eye. What are the functions of HEPES as a common cosmetic ingredient in cosmetics

    HEPES is a zwitterionic buffer, belonging to good's buffer, with a pH buffer range of 6.8-8.2. HEPES buffer is often used in the research of organelles and highly variable, pH-sensitive proteins and enzymes, as well as biochemical diagnostic kits, DNA/RNA extraction kits and PCR diagnostic kits. Because 4-hydroxyethylpiperazine ethanesulfonic acid (HEPES) has the characteristics of safety and mildness, EWG green certification is level 1 (0-2 is green safety level). The EWG certifications of HEPES are all green grades that meet international standards and meet people's needs for "safe and natural" cosmetic ingredients.

    The role of HEPES in cosmetics is manifested in the following aspects:
1. HEPES is known as the new generation PH regulator, which plays a role in maintaining the quality of cosmetics.
The pH value of HEPES adjustment solution ranges from 6.8 to 8.2, which is especially suitable for pH adjustment under physiological conditions. Therefore, in cosmetic solutions, balancing the properties of its more acidic counterparts is the main role of HEPES in cosmetics. .

2. Penetration enhancer to promote the absorption of effective ingredients in cosmetics.
It is well known that only when cosmetics are fully absorbed can they have the effect of skin care and beautification. If the nutrients in cosmetics cannot be completely absorbed, it may cause "skin oxidation" due to excessive nutrition of the epidermis, leading to premature skin aging and skin infections. At this time it is the turn of the booster. Adding penetration enhancers to cosmetics can promote the transdermal absorption of various functional components.

HEPES is such a safe and efficient cosmetic penetration enhancer, which can promote the absorption of nutrients in cosmetics without entering the subcutaneous tissues and circulation in the human body. It not only overcomes the effect of penetration enhancers on the skin in the prior art. The stimulation is fast, and the effect is fast, and the efficiency of promoting penetration is high. HEPES is added to various cosmetics such as Garnier Blemish Essence and Armani Light Key Toner. This may be one of the reasons why such skin care products are effective.

3. HEPES has the function of softening cutin and promoting cell renewal.
HEPES, a weak acid system, is similar to macromolecular fruit acid, which has the effect of softening cutin and promoting cell metabolism. It is widely used in whitening and lightening (Vichy Magic Water, L'Oreal Rejuvenating Centella Micro Essence), anti-aging skin care products (Lancome Black Bottle, YSL Night Queen Essence). It interacts with other ingredients and can be gently removed Old keratinocytes effectively promote the renewal of basal cells to achieve smooth, soft skin and brighten skin tone.

HEPES also has the effects of synergistic sun protection, strengthening the skin barrier, etc., which is popular with sensitive skin. The skin care essence and Kiehl's night renewing cream. Because of the addition of HEPES, it can improve the rough skin texture and relieve large pores. fully utilize.

In addition to HEPES, tromethamine (Tris) can also be used as cosmetic additives. Desheng has 15 years of R&D and production experience in blood collection tube additives, biological buffers, chemiluminescence reagents, etc., for long-term development, the company only provides customers with high-quality products, and can provide high-quality raw materials such as HEPES and TRIS.