Here is the effect of HEPES on cosmetics

Details:

【Name】2-[4-(2-hydroxyethyl)piperazin-1-yl]ethanesulfonic acid

【CAS#】7365-45-9

【Molecular weight】238.305

【Molecular formula】C8H18N2O4S

【Molecular structure】

Hepes4 hydroxyethyl piperazine ethanesulfonic acid is a widely used biological buffer, which can control the pH constant of the system for a long time. The pH buffer range is 6.8-8.2, PKA is 7.48 (25 ℃), and it does not bind with Mg2 +, Ca2 + and other metal cations. It is very suitable for the microbial fermentation extract to maintain its activity, and helps to stabilize the activity of peptides, nucleic acids and fermentation extract, Therefore, it is often used in cosmetics to stabilize the pH value of products with three-year shelf life.

HEPES buffer

It exists in whitening, repairing, anti-aging, fruit acid and other cosmetic products, because HEPES has weak acidity, which can mildly destroy desmosomes connecting keratinocytes, promote colloid exfoliation, smooth and soft skin, brighten skin color and promote whitening. The skin edema was induced by artificial injection of 21 μ HEPES (about 5 g / L) can produce anti-inflammatory effect.

In addition, HEPES is also a safe and efficient penetration enhancer, which can promote the absorption of nutrients in cosmetics gently and quickly, and has high penetration efficiency. The general culture medium containing 20 mmol / L (about 4.77 g / L) HEPES can play a good buffer effect and has no toxic effect on cells. Someone has done experiments, containing 2%HEPES mask solution, and 12 people (2 of them are sensitive skin) used 2 times a week and lasted for 1 months. None of them showed irritation. It proved that its safety is very reliable, and this is why many big brands love it.

Hubei xindesheng Materials Co., Ltd. has been specialized in the research and development of biological buffer solutions for decades. Now it produces a series of biological buffer solutions such as Tris, HEPES, taps, mops, caps, bicine, EPPs and PEP for customers to choose. The price is favorable and the supply is sufficient. There is also a professional after-sales team for you to answer questions, if necessary, please feel free to contact us!