Tris (hydroxymethyl) aminomethane basic knowledge

Details:

Title：Tris  CAS77-86-1

【Name】Trometamol

【Abbreviation】Tris

【CAS#】77-86-1

【Molecular weight】121.135

【Molecular formula】C4H11NO3

【Storage Conditions】Room temperature, light-proof and moisture-proof

【Appearance】White crystal powder

【Molecular structure】

【Use】

1. Tris is used in cosmetics. As a mild and safe cosmetic additive, it is common in some high-end cosmetics, covering Japan, South Korea, Europe and the United States.

2. Tris is used in pharmaceutical intermediates: it can form water-soluble complex salts with insoluble drugs with acidic groups, and the representative drugs are dextrorofen tromethamine, ketorolac tromethamine, etc.

1. Tris is used for activated carbon adsorption: because activated carbon has porous structure and large surface area, when the gas passes through the activated carbon and fully contacts with it, the pollutants are trapped in the pores, so as to achieve the purpose of purifying the gas. Tris can be used to prepare indoor formaldehyde adsorption materials.

4  TRIS is used as pharmaceutical excipient: three hydroxymethyl ammonium methane (TRIS) is used as an alkaline drug for correction of acidosis, and it does not cause carbon dioxide retention.

5. It is widely used as a solvent for nucleic acids and proteins;

6. The low ionic strength of Tris buffer can also be used for the formation of intermediate fibers;

7. The "Te buffer" was prepared by adding EDTA into Tris hydrochloric acid buffer, which can be used for DNA stabilization and storage;

【Advantage】The purity (> 99%) is water-soluble and the process is stable.

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