What is the role of Tris buffer in the field of medicine?

Details:

Tris full name: trimethylol aminomethane, is a kind of biological buffer, which is mostly used in chemical experiments. Tris also plays an important role in the field of medicine. In the following, we will discuss the role of Tris buffer in the field of medicine.

1. Basic information of Tris buffer

Purity: ≥ 99%.

CAS: 77-86-1.

Effective buffer range: 7.2 – 9.0.

pKa（25 ° C）：7.8 – 8.2。

Appearance: white powder.

Molecular formula: C   four   H   eleven   NO   3。

EC No. 201-064-4.

It interacts with the following elements: Cr, Fe, Co, Ni and Cu.

Weak interactions with Mg, CA, Zn, CD and Pb.

2. The role of Tris buffer in the field of Medicine

When preparing the Laemmli buffer, it is one of the least popular biological buffers for SDS-PAGE.

As a binding buffer and eluent in anion exchange chromatography.

It is used to evaluate bacterial endotoxin.

Used as a pH buffer for enzymes in biotechnology.

It is used to purify biological molecules, such as monoclonal antibodies, recombinant proteins and insulin for medical applications.

3. Application of Tris buffer in medicine

Tris is commonly used as a buffer for vaccines and antibiotics such as fosfomycin butyrate.

Tris is considered to be an excellent emulsifier and viscosity control agent, and is known for its ability to retain primary colors after opening.

For inflammation and pain after ophthalmic surgery.

As a biological buffer in drug excipients, it is usually used in high-risk applications.

It is used as an excipient in biological agents and small molecule drugs.

It can be used in eye drops and local drug products to buffer and neutralize.

Used as a biological buffer in skin and sunscreen formulations.

The above are some technical applications of Tris buffer in the field of medicine, and Tris buffer has more and more applications, and the market demand is also growing. High quality Tris buffer is rare, and here we recommend a company: Hubei xindesheng Material Co., Ltd.

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