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Supply 1247825-37-1 low price 1247825-37-1 USP7-USP47 inhibitor good supplier
Supply 1247825-37-1 low price 1247825-37-1 USP7-USP47 inhibitor good supplier

Supply 1247825-37-1 low price 1247825-37-1 USP7-USP47 inhibitor good supplier

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1 Gram

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  • Min.Order :1 Gram
  • Purity: 98%
  • Payment Terms : T/T,Other

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Supply 1247825-37-1 low price 1247825-37-1 USP7-USP47 inhibitor good supplier

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  • Appearance:Powder
  • Application:Scientific research
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  • ProductionCapacity:1000|Gram|Week
  • Storage:keep sealed and keep from direct light
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Supply low price USP7-USP47 inhibitor good supplier

USP7-USP47 inhibitor is a dual inhibitor of ubiquitin-specific protease 7 (USP7) and USP47 (IC50s = 0.42 and 1 μM, respectively). It is selective for USP7 and USP47 over USP2, USP5, USP8, USP21, USP28, caspase-3, and cathepsin B (IC50s = >31.6 μM). USP7-USP47 inhibitor inhibits the growth of HCT116 cells (EC50 = 7.6 μM).

USP7-USP47 inhibitor is a dual inhibitor of ubiquitin-specific protease 7 (USP7) and USP47 (IC50s = 0.42 and 1 µM, respectively). It is selective for USP7 and USP47 over USP2, USP5, USP8, USP21, USP28, caspase-3, and cathepsin B (IC50s = >31.6 µM). USP7-USP47 inhibitor inhibits the growth of HCT116 cells (EC50 = 7.6 µM). Formal Name: 4-cyano-5-[(3,5-dichloro-4-pyridinyl)thio]-N-[4-(methylsulfonyl)phenyl]-2-thiophenecarboxamide. CAS Number: 1247825-37-1. Molecular Formula: C18H11Cl2N3O3S3. Formula Weight: 484.4. Purity: >98%. Formulation: A crystalline solid. Solubility: DMSO: 44 mg/ml. lambdamax: 237, 326 nm. SMILES: CS(C1=CC=C(NC(C2=CC(C#N)=C(SC3=C(Cl)C=NC=C3Cl)S2)=O)C=C1)(=O)=O. InChi Code: InChI=1S/C18H11Cl2N3O3S3/c1-29(25,26)12-4-2-11(3-5-12)23-17(24)15-6-10(7-21)18(27-15)28-16-13(19)8-22-9-14(16)20/h2-6,8-9H,1H3,(H,23,24). InChi Key: GUDJFFQZIISQJB-UHFFFAOYSA-N.

Details:

Alternate Name 4-cyano-5-[(3,5-dichloro-4-pyridinyl)thio]-N-[4-(methylsulfonyl)phenyl]-2-thiophenecarboxamide
Peptide Sequence N/A
Appearance Crystalline solid
CAS # 1247825-37-1
Molecular Formula C??H??Cl?N?O?S?
Molecular Weight 484.4
Purity ≥ 98% by HPLC
Solubility >40 mg/ml in DMSO
SMILES CS(C1=CC=C(NC(C2=CC(C#N)=C(SC3=C(Cl)C=NC=C3Cl)S2)=O)C=C1)(=O)=O
InChi InChI=1S/C18H11Cl2N3O3S3/c1-29(25,26)12-4-2-11(3-5-12)23-17(24)15-6-10(7-21)18(27-15)28-16-13(19)8-22-9-14(16)20/h2-6,8-9H,1H3,(H,23,24)
InChi Key GUDJFFQZIISQJB-UHFFFAOYSA-N
PubChem CID 51031028
Handling Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Storage Conditions -20ºC
Shipping Conditions Gel Pack
USAGE For Research Use Only! Not For Use in Humans.

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