61276-17-3 Verbascoside Wholesaler 61276-17-3 low price Acteoside factory sells

Min.Order / FOB Price:Get Latest Price

1 Metric Ton	FOB Price: USD 8.0000

1 Metric Ton

FOB Price: USD 8.0000

Min.Order :1 Metric Ton
Purity: 90%,40%,60%.80%
Payment Terms : T/T,,MoneyGram

Keywords

61276-17-3 Verbascoside Wholesaler 61276-17-3 low price Acteoside factory sells

Quick Details

Appearance:brown powder
Application:health food ingredient
PackAge:1kg/pack,25kg/drum
ProductionCapacity:100000|Kilogram|Year
Storage:dry and cool place
Transportation:by ems,air,UPS,FEDEX

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61276-17-3 Verbascoside Wholesaler low price Acteoside factory sells

Verbascoside is isolated from Lantana camara, acts as an ATP-competitive inhibitor of PKC, with an IC50 of 25 µM, and has antitumor, anti-inflammatory and antineuropathic pain activity.

Verbascoside is a natural phenylpropanoid glucoside that has been found in a variety of plants, including B. cordata, B. officinalis, and S. vulgaris, and has diverse biological activities. Verbascoside is a PKC inhibitor (IC₅₀ = 25 μM).It inhibits the growth of Gram-positive and Gram-negative bacteria with MIC values ranging from 4 to 128 μg/ml including S. aureus and E. coli (MICs = 16 and 32 μg/ml, respectively). Verbascoside (0.1-10 μg/ml) dose-dependently reduces extracellular hydrogen peroxide concentrations and increases cell viability of PC12 cells following 1-methyl-4-phenylpyridinium ion (MPP⁺) administration to induce apoptosis and oxidative stress. It also inhibits the growth of MGC803 human gastric adenocarcinoma cells in a dose-dependent manner when used at concentrations ranging from 10 to 20 μM with maximal growth inhibition of 53%. In a rat model of colitis induced by 2,4-dinitrobenzene sulfonic acid (DNBS), verbascoside (0.2-2 mg/kg) reduces colon damage and the expression of TNF-α, IL-1β, and inducible nitric oxide synthase

Details:

Medchemexpress, HY-N0021 10mg Verbascoside CAS:61276-17-3 Verbascoside is isolated from Lantana camara, acts as an ATP-competitive inhibitor of PKC , with an IC 50 of 25 µM, and has antitumor, anti-inflammatory and antineuropathic pain activity. Purity:>98% Medchemexpress has over 10000 novel life-science reagents, reference compounds, APIs and natural compounds for laboratory and scientific use. Other quantity can also be offered.

Product name
Verbascoside, PKC inhibitor
Description

PKC inhibitor. NF-κB inhibitor.
Biological description

PKC inhibitor. NF-κB inhibitor. Increases PARP-1 and p53. Induces cell cycle arrest and differentiation. Inhibits MMP (IC₅₀ = 32 μM). Shows anti-inflammatory, antinociceptive and antioxidant effects in vivo. Orally active.
Purity

> 98%
CAS Number

61276-17-3
Chemical structure

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