SAM Ademetionine 101020-79-5
Assay: 90% up by GC;
Stable supply with over 20Mt annually;
Ademetionine 1,4-butanedisulfonate
Product Information
Product Name | Ademetionine 1,4-butanedisulfonate |
CAS No. | 101020-79-5 |
Molecular Formula | C23H41N6O17S5- |
Molecular Weight | 833.91 |
Usage | Treatment of intrahepatic cholestasis before and during cirrhosis. Treatment of intrahepatic cholestasis during pregnancy. |
Reference COA
ITEMS | STANDARDS | RESULTS |
Appearance | A white or almost white powder | White powder |
Solubility | Freely soluble in water, practically insoluble in ethanol and in acetone. | Conforms |
Identification | 1. The gas it produced can make wet potassium iodate test pater show blue. | Conforms |
2. UV: it has absorption maximum at the 258nm | ||
3. HPLC: the retention time of the principal peak in the chromatogram obtained with test solution is in accordance with that of the reference. | ||
pH | 2.1~2.5 | 2.4 |
Clarity and color of solution | Color: ≤Y3# or YG3# | Conforms |
A solution should be clear. | ||
Isomers | (S,S-Isomer) ≥70% | 74.00% |
Related substances | Adenine≤0.4% | 0.05% |
S-Adenosyl-L-Homocysteine≤0.4% | 0.09% | |
Methylthioadenosine≤2.0% | 0.43% | |
Decarboxylation adenosine methionine≤1.2% | 1.00% | |
The other unknown impurities≤1.0% | 0.05% | |
Total of impurities≤4.0% | 1.80% | |
Water | ≤6.0% | 2.40% |
Residual solvents | Ethyl acetate≤5000ppm | Conforms |
Microbial limit tests | Bacteria≤1000cfu/g | Conforms |
Bacterial endotoxins | ≤0.438 EU/mg | Conforms |
Content (dried basis) | Butanedisuphonic acid: 46.0~51.0% | 47.20% |
Adenosine methionine: 48.0~53.0% | 52.20% | |
Total≥96.0% | 99.40% | |
Conclusion | Conforms to enterprise standard |
About SINOWAY
Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc..
We have passed ISO9001:2015. With qualified products, competitive price and excellent service, we have received great reputation of our customers from all over the world, including Southeast Asia, Europe, North America, South America, Middle East and other countries. We have over 20 years good partners in Japan、Korea and Switzerland.
Sinoway has a professional R&D team. We have built close cooperative relationships with many research institutes and universities in China. Moreover, Sinoway combines market analysis with technology, providing new business trends to our clients.
In addition, we have very close cooperation relationships with many Chinese pharmaceutical factories. These pharmaceutical manufacturers have GMP regulated workshops, advanced production and testing equipments, first-class QC labs and a production team with rich experience. We can supply various Active Pharmaceutical Ingredients and finished products which meet EP/USP/BP standards. Chinese GMP, EU-GMP, COS/CEP certificates with DMF documents are available, and many products have been approved by FDA.
We believe that quality and innovation are vital for an enterprise. Adhering to the business philosophy of integrity and win-win cooperation, Sinoway is looking forward to have a bright future with you together.
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