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NADP 53-59-8 Nicotinamide adenine dinucleotide phosphate
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NADP Nicotinamide adenine dinucleotide phosphate (53-59-8) | |
β-Nicotinamide adenine dinucleotide phosphate is a common form of NADP which acts as an electron acceptor. | |
Name | NADP Monosodium Salt |
CAS | 53-59-8 |
Purity | 95% |
Chemical name | β-Nicotinamide adenine dinucleotide phosphate |
Synonyms | β-NADP, Coenzyme II, TPN, NADP, Triphosphopyridine nucleotide |
Molecular Formula | C21H28N7O17P3 |
Molecular Weight | 743.41 (anhydrous basis) |
Form | Solid |
EINECS | 200-178-1 |
Appearance | White powder |
Solubility | Soluble in water (50 mg/ml), methanol, and ethanol. Insoluble in ether, and ethyl acetate |
Application | IVD ,Enzymatic synthesis |
Testing Document | Available |
Storage Condition | Keep dry ,away from light, and store at 2℃- 8℃, long term store at -15℃ to -25℃ |
Package | 10gram/bag ,50gram/bag , 1KG/bag, 25KG/drum |
Application | |
β-Nicotinamide adenine dinucleotide phosphate hydrate is suitable for use in: | |
the measurement of Glucose-6-phosphate dehydrogenase activity | |
the Cytochrome P450 3A4 assay as a part of NADPH-regenerating system | |
the Cytochrome P450 2D6 assay as a part of NADPH-regenerating system | |
the determination of Glucose-6-phosphate content | |
Biochem/physiol Actions | |
β-Nicotinamide adenine dinucleotide 2′-phosphate (NADP+) and β-Nicotinamide adenine dinucleotide 2′-phosphate, reduced (NADPH) comprise a coenzyme redox pair (NADP+:NADPH) involved in a wide range of enzyme catalyzed oxidation reduction reactions. The NADP+/NADPH redox pair facilitates electron transfer in anabolic reactions such as lipid and cholesterol biosynthesis and fatty acyl chain elongation. The NADP+/NADPH redox pair is used in a variety of antioxidation mechanism where it protects agains reactive oxidation species accumulation. NADPH is generated in vivio by the pentose phosphate pathway (PPP). | |
Electron acceptor |
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