Telmisartan Telmisartan powder 144701-48-4
We are very compeitive on Telmisartan.Our mfr is GMP certified for this item with CEP document.
Telmisartan, 4'-[(1,4'-dimethyl-2'-propyl[2,6'-bi-1H-benzimidazol]-1'-yl)methyl]-[1,1'-biphenyl]-2-carboxylic acid (Micardis), does not appear to bear any structuralrelationship to this class, but there is actually a great dealof overlap in the chemical architecture with other agents. Thefirst, and most significant, difference is the replacement of theacidic tetrazole system with a simple carboxylic acid. Thisacid, like the tetrazole, plays a role in receptor binding. Thesecond difference is the lack of a carboxylic acid near the imidazolenitrogen that also contributes to receptor binding.As with irbesartan, however, there is not a need for this groupto be acidic but, rather, to be one that participates in receptorbinding. The second imidazole ring, much like a purine basein deoxyribonucleic acid (DNA), can hydrogen bond with theangiotensin II receptor.
Product Name: | Telmisartan |
CAS: | 144701-48-4 |
MF: | C33H30N4O2 |
MW: | 514.62 |
EINECS: | 620-494-7 |
Product Categories: | CARADRIN;Pharmaceutical material and intermeidates;INTERMEDIATESOF;Imidazoles;(intermediates of telmisartan);Telmisartan;Active Pharmaceutical Ingredients;Antihypertensive;Hypertension;Intermediates & Fine Chemicals;Pharmaceuticals;API's;Other Products;Hypertension. |
Mol File: | 144701-48-4.mol |
Melting point | 261-263°C |
Boiling point | 771.9±70.0 °C(Predicted) |
density | 1.16 |
RTECS | DV2037500 |
storage temp. | 2-8°C |
solubility | DMSO: >5 mg/mL at 60 °C |
form | solid |
pka | 3.86±0.36(Predicted) |
color | white |
Water Solubility | insoluble |
Merck | 14,9129 |
InChIKey | RMMXLENWKUUMAY-UHFFFAOYSA-N |
CAS DataBase Reference | 144701-48-4(CAS DataBase Reference) |
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