factory supply GMP,DMF Tenofovir Disoproxil Fumarate

factory supply GMP,DMF Tenofovir Disoproxil Fumarate

Min.Order / FOB Price:Get Latest Price

1 Kilogram	Negotiable

1 Kilogram

Negotiable

Min.Order :1 Kilogram
Purity: USP/EP/BP
Payment Terms : L/C,T/T,Other

Keywords

Tenofovir Disoproxil Fumarate TDF 202138-50-9

Quick Details

Appearance:White crystallization
Application:anti- Virus response
PackAge:1kg/tin
ProductionCapacity:1|Metric Ton|Day
Storage:
Transportation:AIR SEA TRAIN

Superiority:

We are very compeitive on Tenofovir Disoproxil Fumarate.Our mfr is GMP certified for this item with DMF document.

Product Name:	Tenofovir disoproxil fumarate
Synonyms:	TDF
CAS:	202138-50-9
MF:	C23H34N5O14P
MW:	635.52
EINECS:	687-766-5
Product Categories:	Bases & Related Reagents;Intermediates & Fine Chemicals;Nucleotides;Pharmaceuticals;Phosphorylating and Phosphitylating Agents;Inhibitors;Tenofovir;API
Mol File:	202138-50-9.mol

Details:

Overview

Tenofovir disoproxil fumarate, a prodrug of tenofovir[Trade name: “Viread”] developed by Gilead Sciences, is a kind of nucleotide-analogues antiretroviral drugs, taking effect through acting as the reverse transcriptase inhibitors[nRTIs], which block reverse transcriptase, an enzyme crucial to viral production in HIV-infected people^[1-4]. It should be noted that it is the first nucleotide reverse transcriptase inhibitor that has ever used for the treatment of HIV infection^[5]. Tenofovir disoproxil fumarate is converted to tenofovir in vivo, which is an acyclic nucleoside phosphonate[nucleotide] analog of adenosine 5'-monophosphate^[5,6]. It is generally used in combination with other kinds of medicine. HIV medicines can't cure HIV/AIDS, but taking a combination of HIV medicines[called an HIV regimen] every day can help people with HIV live longer, healthier lives^[7]. Based on the FDA document, tenofovir disoproxil fumarate can also be for the treatment of chronic hepatitis B virus[HBV] infection in adults and children 12 years of age and older^{[1,3, 4, 8]}.

Indication and application

Tenofovir disoproxil fumarate[trade name: Viread®], an antiviral drug, is indicated as the treatment for both HIV and Hepatitis B virus[HBV]. Viread® is indicated in combination with other antiretroviral agents for the treatment of HIV-1 infection in adults and pediatric patients 2 years of age and older. It is also indicated for the treatment of chronic hepatitis B in adults and pediatric patients 12 years of age and older

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