Polymyxin B Sulphate CAS:1405-20-5

Details:

Sinoway Industrial co., ltd. was established in 1987 in Xiamen, China, and now has been a leading group specialized in research, development, custom manufacturing and trading of pharmaceutical intermediates, APIs, health and food supplements, cosmetic raw materials, herbal extracts, polypeptides and prostaglandin derivatives, etc..

Function of Polymyxin B Sulphate

Polymyxin B sulphate is similar to polymyxin E. It can inhibit gram-negative bacilli such as Escherichia coli, Pseudomonas aeruginosa, Para Escherichia coli, Klebsiella pneumoniae, Acidophilus, Pertussis and Shigella, etc. Or bactericidal effect. It is mainly used for Pseudomonas aeruginosa and other Pseudomonas to cause the wounds, urinary tract, eyes, ears, trachea and other parts of the Chemicalbook infection. It can also be used for sepsis and peritonitis. And resistant to aminoglycosides, resistant to third-generation cephalosporin bacteria and Pseudomonas aeruginosa or other sensitive bacteria caused by serious infections, such as bacteremia, endocarditis, pneumonia, post-burn infections, etc.

Polymyxin B is a peptide antibiotic against gram-negative bacilli, which can change the membrane structure to leak small molecules and inhibit the growth of gram-negative bacteria. Has a bactericidal effect on E. coli Chemicalbook. Binds to the lipid A portion of bacterial lipopolysaccharides. Inducing small holes in the outer cell membrane. Mode of action: Combine and interfere with the permeability of the cell plasma membrane. Antibacterial spectrum: Gram-negative bacteria.