Application of potassium EDTA

Details:

When it comes to EDTA, many people should have heard of it. Today I'll introduce you to the two potassium salts used in blood coagulants

Let's get to know:

Dipotassium EDTA, alias: dipotassium EDTA CAS No.: 25102-12-9, molecular weight: 404.46, molecular formula:

C10H18K2N2O10

Potassium EDTA, alias: potassium EDTA CAS No.: 65501-24-8, molecular weight: 442.54

Where: c10h13k3n2o8

Application of EDTA dipotassium in practice: additive of vacuum blood collection vessel, preparation of toilet deodorant, use as complexing agent in liquid phase analysis

Preparation of metal polishing agent

The practical application of potassium EDTA is used to complex metal ions and separate metals, and to prepare anticoagulants, anticoagulant tubes and

A whole blood analyzer; It is also used in detergents, liquid soap, shampoo, agricultural chemical spray, antidote and anticoagulant.

Wait.

We can see that both dipotassium EDTA and Tripotassium EDTA are commonly used anticoagulants in blood collection, and the anticoagulant principle is used

EDTA is used to chelate Ca ions in the blood, so as to prevent the anticoagulant effect. Both are white crystalline powders, insoluble in water,

Slightly soluble in alcohol, used for preparing anticoagulant and anticoagulant tube, used with whole blood analyzer. But when we look closely, we find that three potassium is higher than two potassium

One more potassium ion.

Although both of them use blood collection anticoagulants, their anticoagulant ability is different, mainly in the complexation of ca

It is precisely because of the difference in the use of edta-ka2 in 5% aqueous solution

The pH value of edta-ka3 is 4.8 ± 1, and the pH value of edta-ka3 is 7.3 ± 1. The difference is mainly reflected in different pH

Stable under. Edtak3ph value is neutral and will not affect the pH value of blood. At the same time, its ability to complex calcium ions is higher than

EDTAK2 is stronger, and the anticoagulant effect is a little stronger than EDTAK2; At the same time, the solubility of dipotassium is lower than that of Tripotassium, which sometimes affects the resistance to oxidation

Coagulation effect; However, if edtak3 is used as a liquid additive, it will cause dilution of the sample. All direct test items,

Such as hemoglobin, red blood cell, white blood cell and platelet count, which is 1 ~ 2% lower than EDTAK2 as anticoagulant.

So it seems that whether you choose two potassium or three potassium, there are both advantages and disadvantages. The main thing is to choose what is suitable for you. We Hubei De

Sheng is a professional manufacturer of blood collection additives. It has been produced in this area for more than ten years. The production process is mature and the technology refers to

The standard is excellent and worthy of your trust!