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Clozapine factory price High purity 99%
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Product Information
product name | Clozapine |
CAS | 5786-21-0 |
MW | 326.823 |
Density | 1.3±0.1 g/cm3 |
MF | C18H19ClN4 |
Assay | 99% |
MP | 182-185°C |
BP | 489.2±55.0 °C at 760 mmHg |
fp | 249.6±31.5 °C |
Usage
Description
Clozapine is a pale yellow crystalline powder.No smell, no smell.Soluble in trichloromethane, soluble in ethanol, hardly soluble in water.Also Known as 8-chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine.Clozapine is widely used in the control of insomnia, depression, epilepsy and other neurological diseases. This product is a non-classical antipsychotic which can selectively block DA receptors of the mesolimbic system but has a small effect on the nigrostriatal DA receptors. It has a relatively weak blocking effect on D2 receptor, but a strong blocking effect on D1 receptors strong while also has some antagonist effect on D4 receptor and 5-HT2 receptor. Thereby, it has strong anti-psychotic effects.
Function
1. Used for acute, chronic mania. It can be used to stabilize the emotion of human. It has good efficacy on symptoms like, vagrancy, sleep disorder, sadness, panic, tiredness, easy to be ill, sudden violence, and anger;
2. Can be used for crazy disease due to a variety of reasons such as losing temper, aggressive, emotional instability, anxiety, tension, and manic, etc;
3. Can be used for mental retardation-caused behavioral disorders such as linguistic disorder, poor presentation ability, poor thought and mental ability.
COA OF Clozapine
Items |
Specification |
Result |
Appearance |
Yellow crystalline powder |
Yellow crystalline powder |
Identification |
Positive |
Positive |
Melting point |
182 ~ 186 |
183.5 ~ 185.5 |
Related substances |
Impurity A NMT 0.1% |
0.01% |
Impurity B NMT 0.2% |
0.03% |
|
Impurity C NMT 0.3% |
0.04% |
|
Impurity D NMT 0.2% |
0.02% |
|
Unspecified impurity NMT 0.1% |
0.01% |
|
Total impurity NMT 0.6% |
0.1% |
|
Heavy metals |
NMT0.002% |
NMT0.001% |
Loss on drying |
NMT 0.5% |
0.03% |
Sulfate ash |
NMT 0.1% |
0.02% |
Assay |
99.0 ~ 101.0% |
99.6% |
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