CasNo.8025-81-8,factory supply GMP,DMF,CEP Spiramycin,(8025-81-8) Suppliers

1 Kilogram	Negotiable

Min.Order :1 Kilogram
Purity: USP/EP/BP
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Keywords

Spiramycin foromacidin 8025-81-8

Quick Details

Appearance:White crystallization
Application:Cardiovascular APIs,Sartan antihypertensive drugs
PackAge:25kg/drum
ProductionCapacity:10|Metric Ton|Day
Storage:room temperature
Transportation:AIR SEA TRAIN

Superiority:

We are very compeitive on Spiramycin.Our mfr is GMP certified for this item with CEP document.

Product Name:	Spiramycin
Synonyms:	SPIRAMYCIN;rovamycin;provamycin;FORMACIDINE;foromacidin;LEUCOMYCIN;KITASAMYCIN BASE;Spiramycin Ep
CAS:	8025-81-8
MF:	C43H74N2O14
MW:	843.05
EINECS:	232-429-6
Product Categories:	Pharmaceutical intermediates;Inhibitors;Miscellaneous Natural Products;Antibacterial;Antibiotics for Research and Experimental Use;Peptide Synthesis/Antibiotics;Biochemistry;Macrolides (Antibiotics for Research and Experimental Use);MacrolidesAntibiotics;MLSAlphabetic;SN - SZMore...Close...;Antibiotics;Antibiotics A to;Macrolides;Antibiotics N-SAntibiotics;BactericidalAntibiotics;Chemical Structure;Chemical Structure Class;Interferes with Protein SynthesisSpectrum of Activity;L - ZAntibiotics;Mechanism of Action;Principle;S
Mol File:	8025-81-8.mol

Details:

Spiramycin Chemical Properties

Melting point	126-128 °C
alpha	D20 -80° (methanol)
Boiling point	914℃
refractive index	81 ° (C=2, 10% AcOH)
Fp	>110°(230°F)
storage temp.	2-8°C
solubility	ethanol: 50 mg/mL, clear to slightly hazy, light-yellow
form	powder
color	white to light yellow
optical activity	[α]/D -85 to -80° in water (Specific rotation (dry basis))
Water Solubility	Soluble in methanol. Slightly soluble in water
Merck	14,8752
CAS DataBase Reference	8025-81-8

Uses

Spiramycin I (foromacidin A) is the major analogue of a complex of 16-membered macrocyclic lactones produced by S. ambofaciens and S. spiramyceticus that have broad spectrum antibiotic activity. Spiramycins are unusual among the macrocyclic lactones in that they contain two basic sugars. Spiramycin complex has been used in both human and animal health but its use has not been widespread.

Manufacturing Process

The process for producing spiramycin comprises inoculating an aqueous nutrient medium with a culture of the NRRL No. 2420, allowing aerobic fermentation to take place and separating from the culture medium the spiramycin thus formed. The culture medium also contains the antibiotic substance known as Congocidin which, however, does not possess the same useful properties as spiramycin and which can be isolated in crystalline form. The separation of the two antibiotic substances is readily achieved.