IMATINIB MESYLATE C...

IMATINIB MESYLATE CAS:220127-57-1

IMATINIB MESYLATE CAS:220127-57-1

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1 Kilogram

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  • Min.Order :1 Kilogram
  • Purity: 99%
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Keywords

Imatinib Mesylate powder CAS:220127-57-1 Imatinib Mesylate Anticancer API Imatinib Mesylate

Quick Details

  • Appearance:White or slightly yellow crystalline powder,
  • Application:Anticancer
  • PackAge:1kg/tin or per customer's requirement
  • ProductionCapacity:1000|Kilogram|Month
  • Storage:
  • Transportation:

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3) Accept better payment terms : T.T 30-60 days.on the basic of pass SINOSURE credit investigation.

5) We have warehouse in USA with quickly shipment .

6) We can do different terms of FOB ,CIF/CIP ,DDP ...

Details:

Product Information

Product name

Imatinib Mesylate

Molecular Formula

C30H35N7O4S

Molecular Weight

589.71

CAS No.

220127-57-1

Quality Standard

In-house standard

Appearance

White powder

 

COA of Imatinib Mesylate

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SPECIFICATION

RESULTS

Appearance

White or slightly yellow crystalline powder, 
homogeneous and with fine grain size. 
No foreign particles are observed.

Slightly yellow crystalline Powder

Solubility

Soluble in water and in acids solutions, slightly soluble 
in methanol insoluble in acetone, acetonitrile and 
dilute hydroxyl alkaline solution

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Identification

Complies

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Water

≤1.0%

0.8%

Heavy metals

≤20ppm

10ppm

Melting range

212 – 220℃

214-216℃

Residue on ignition

≤0.1%

0.08%

Particle size

90% < 100 μm

50% < 50 μm

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Bulk density

NLT 0.4g/ml

0.6g/ml

Chromatographic

purity

Individual impurities: ≤0.2%

Total impurities: ≤0.5%

0.16%

0.32%

Assay

98.5%-102.0% of Imatinib mesylate,

calculated on anhydrous basis.

99.70%

 

 

Residual solvents

Ethyl acetate: ≤5000ppm

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Acetone: ≤5000ppm

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N,N-Dimethylformamide: ≤880ppm

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Methanol: ≤3000ppm

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Dichloromethane: ≤300ppm

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We provide you with high-quality imatinib mesylate powder and imatinib mesylate price is very reasonable and competitive.

 

Usage

Imatinib mesylate (also called Gleevec) is a small-molecule inhibitor of the fusion protein Bcr-Abl, the causal agent in chronic myelogenous leukemia. As an inhibitor of PDGFR, imatinib mesylate appears to have utility in the treatment of a variety of 
dermatological diseases. Imatinib has been reported to be an effective treatment for FIP1L1-PDGFRalpha+ mast cell disease, hypereosinophilic syndrome, and dermatofibrosarcoma protuberans.

1. A tyrosine kinase inhibitor. Highly specific for BCR-ABL, the enzyme associated with chronic myelogenous leukemia (CML) and certain forms of acute lymphoblastic leukemia (ALL)

2. Echinocandin antifungal, active against infections with Aspergillus and Candida, inhibits cell wall synthesis

3. Anticancer

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