CasNo.192725-17-0,Factory Supply Raw Material Lopinavir Powder,(192725-17-0) Suppliers

1 Metric Ton	FOB Price:USD 10.0000 -1350.0000

Min.Order :1 Metric Ton
Purity: 99% up
Payment Terms : L/C,D/A,D/P,T/T,Other

Keywords

Lopinavir factory price High purity 99%

Quick Details

Appearance:White powder
Application:Lopinavir is used in combination with ...
PackAge:1kg/bag ;5kg/drum:25KG/drum
ProductionCapacity:20|Metric Ton|Month
Storage:in low tempreture
Transportation:in low tempreture

Superiority:

Why is SINOWAY:

1) Specialized in pharmaceutical and healthcare industrial for 34 years.

2) ISO 9001:2015 & SGS audited supplier .

3) Accept various payment terms : T.T 30-60 days.

4) We have warehouse in USA with quickly shipment .

5) We can do different terms of FOB ,CIF/CIP ,DDP ...

Why choose us

1. best quality in your requirement
2. competitive price in china market
3. mature technical support
4. professional logistic support
5. full experience of large numbers containers loading in chinese sea port
6. fast shipment by reputed shipping line
7. packing with pallet as buyer's special request
8. best service after shipment with email !
9. cargoes together with container after-sales service available
10. full experience in export
11. raw materials from chinese origin

Details:

Product Information

Product name	Lopinavir
CAS No.	192725-17-0
Molecular Formula	C37H48N4O5
Molecular Weight	628.801
Quality Standard	99% up, USP42, Medicine Grade
Appearance	White powder

COA

TEST	SPECIFICATION	RESULTS
Description	White powder	Complies
Identification	IR	Complies
	HPLC	Complies
Heavy metal	≤10ppm	5ppm
Pb	≤3ppm	1.5ppm
Hg	≤0.1ppm	0.05ppm
Cd	≤1ppm	0.2ppm
Loss on drying	≤0.5%	0.12
Residue on lgnition	≤0.1%	0.03
Single impurity	≤0.5%	0.12
Total impurity	≤1.0%	0.29
Total bacteria	≤1000cfu/g	<1000
Yeast and Mould	≤100 cfu/g	<000
E.coli/25g	Absent	Absent
Salmonella/25g	Absent	Absent
Assay	≥99.0%	99.4%
Conclusion	Conforms with USP/EP standards

Usage

Function of Lopinavir

Lopinavir is used in combination with other antiretroviral drugs to treat human immunodeficiency virus-1 (HIV-1) infection in adults and children over 2 years old.

Lopinavir is an HIV protease inhibitor, which can block the division of Gag-Pol polyprotein, resulting in the production of immature, non-infectious virus particles; ritonavir is a kind of HIV-1 and HIV- 2 Peptidomimetic inhibitors of aspartyl protease activity. By inhibiting HIV protease, the enzyme cannot process the precursor of Gag-Pol polyprotein, resulting in the formation of immature HIV particles, which prevents the start of a new infection cycle. Ritonavir can inhibit CYP3A-mediated metabolism of lopinavir, resulting in a higher concentration of lopinavir.

Antiviral activity of Lopinavir: In vitro antiviral drug activity studies in combination with lopinavir have shown that the combination of lopinavir and nelfinavir will increase the antagonistic effect, and it can be compared with amprenavir, atazanavir and indinavir The combined application of Vivi, Saquinavir and Telanavir will increase the synergy. The EC50 value of lopinavir for three different HIV-2 virus strains is between 12~180nM (0.008~113 μg/mL).